ENSG00000104341


Homo sapiens

Features
Gene ID: ENSG00000104341
  
Biological name :LAPTM4B
  
Synonyms : LAPTM4B / lysosomal protein transmembrane 4 beta / Q86VI4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q22.1
Gene start: 97775057
Gene end: 97853013
  
Corresponding Affymetrix probe sets: 1554679_a_at (Human Genome U133 Plus 2.0 Array)   208029_s_at (Human Genome U133 Plus 2.0 Array)   208767_s_at (Human Genome U133 Plus 2.0 Array)   214039_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000429868
Ensembl peptide - ENSP00000482533
Ensembl peptide - ENSP00000402301
Ensembl peptide - ENSP00000428409
NCBI entrez gene - 55353     See in Manteia.
OMIM - 613296
RefSeq - NM_018407
RefSeq Peptide - NP_060877
swissprot - H0YBN1
swissprot - Q86VI4
Ensembl - ENSG00000104341
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 laptm4bENSDARG00000035870Danio rerio
 LAPTM4BENSGALG00000045196Gallus gallus
 Q91XQ6ENSMUSG00000022257Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q15012 / LAPTM4A / lysosomal protein transmembrane 4 alphaENSG0000006869732


Protein motifs (from Interpro)
Interpro ID Name
 IPR004687  Lysosomal-associated transmembrane protein 4/5
 IPR018401  Lysosomal-associated transmembrane protein 4B


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007032 endosome organization IMP
 biological_processGO:0032509 endosome transport via multivesicular body sorting pathway IDA
 biological_processGO:0032911 negative regulation of transforming growth factor beta1 production IDA
 biological_processGO:0097213 regulation of lysosomal membrane permeability IMP
 biological_processGO:1905166 negative regulation of lysosomal protein catabolic process IMP
 biological_processGO:1905671 regulation of lysosome organization IMP
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0032585 multivesicular body membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0097487 multivesicular body, internal vesicle IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019900 kinase binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0097001 ceramide binding IDA
 molecular_functionGO:1902936 phosphatidylinositol bisphosphate binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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