ENSG00000104626


Homo sapiens

Features
Gene ID: ENSG00000104626
  
Biological name :ERI1
  
Synonyms : ERI1 / exoribonuclease 1 / Q8IV48
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: p23.1
Gene start: 9002147
Gene end: 9116746
  
Corresponding Affymetrix probe sets: 226416_at (Human Genome U133 Plus 2.0 Array)   231852_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000430651
Ensembl peptide - ENSP00000250263
Ensembl peptide - ENSP00000429043
Ensembl peptide - ENSP00000429615
Ensembl peptide - ENSP00000430190
NCBI entrez gene - 90459     See in Manteia.
OMIM - 608739
RefSeq - XM_017013954
RefSeq - XM_011543851
RefSeq - XM_017013949
RefSeq - XM_017013950
RefSeq - XM_017013951
RefSeq - XM_017013952
RefSeq - XM_017013953
RefSeq - NM_001354635
RefSeq - NM_153332
RefSeq - XM_005272401
RefSeq - XM_011543848
RefSeq - XM_011543849
RefSeq - XM_011543850
RefSeq Peptide - NP_001341564
RefSeq Peptide - NP_699163
swissprot - E5RJM3
swissprot - E5RIV7
swissprot - Q8IV48
swissprot - A0A024R355
Ensembl - ENSG00000104626
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eri1ENSDARG00000044692Danio rerio
 ERI1ENSGALG00000011448Gallus gallus
 Eri1ENSMUSG00000031527Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ERI2 / A8K979 / ERI1 exoribonuclease family member 2ENSG0000019667826
ERI3 / O43414 / ERI1 exoribonuclease family member 3ENSG0000011741926


Protein motifs (from Interpro)
Interpro ID Name
 IPR003034  SAP domain
 IPR012337  Ribonuclease H-like superfamily
 IPR013520  Exonuclease, RNase T/DNA polymerase III
 IPR036361  SAP domain superfamily
 IPR036397  Ribonuclease H superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006259 DNA metabolic process IBA
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0031125 rRNA 3"-end processing ISS
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0071204 histone pre-mRNA 3"end processing complex ISS
 molecular_functionGO:0000175 3"-5"-exoribonuclease activity TAS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008408 3"-5" exonuclease activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019843 rRNA binding ISS
 molecular_functionGO:0043022 ribosome binding ISS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0071207 histone pre-mRNA stem-loop binding ISS


Pathways (from Reactome)
Pathway description
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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