ENSMUSG00000031527


Mus musculus

Features
Gene ID: ENSMUSG00000031527
  
Biological name :Eri1
  
Synonyms : Eri1 / exoribonuclease 1
  
Possible biological names infered from orthology : Q8IV48
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: A4
Gene start: 35465253
Gene end: 35496196
  
Corresponding Affymetrix probe sets: 10578193 (MoGene1.0st)   1418827_at (Mouse Genome 430 2.0 Array)   1418828_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033927
Ensembl peptide - ENSMUSP00000148099
Ensembl peptide - ENSMUSP00000147464
NCBI entrez gene - 67276     See in Manteia.
MGI - MGI:1914526
RefSeq - NM_026067
RefSeq Peptide - NP_080343
swissprot - A0A1B0GSW4
swissprot - A0A1B0GRC5
swissprot - A0A0R4J0C8
Ensembl - ENSMUSG00000031527
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eri1ENSDARG00000044692Danio rerio
 ERI1ENSGALG00000011448Gallus gallus
 ERI1ENSG00000104626Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Eri2 / Q5BKS4 / Mus musculus exoribonuclease 2 (Eri2), transcript variant 2, mRNA. / A8K979* / ERI1 exoribonuclease family member 2*ENSMUSG0000003092927
Eri3 / Q8C460 / Mus musculus exoribonuclease 3 (Eri3), transcript variant 6, mRNA. / O43414* / ERI1 exoribonuclease family member 3*ENSMUSG0000003342326


Protein motifs (from Interpro)
Interpro ID Name
 IPR003034  SAP domain
 IPR012337  Ribonuclease H-like superfamily
 IPR013520  Exonuclease, RNase T/DNA polymerase III
 IPR036361  SAP domain superfamily
 IPR036397  Ribonuclease H superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0008408 3"-5" exonuclease activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000352 decreased cell proliferation "less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+,Pdgfratm12Sor/Pdgfra+
Genetic Background: involves: 129 * 129/Sv * C57BL/6J * SJL

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+,Pdgfratm12Sor/Pdgfra+
Genetic Background: involves: 129 * 129/Sv * C57BL/6J * SJL

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+,Pdgfratm12Sor/Pdgfra+
Genetic Background: involves: 129 * 129/Sv * C57BL/6J * SJL

 MP:0004200 reduced fetal size "smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+,Pdgfratm12Sor/Pdgfra+
Genetic Background: involves: 129 * 129/Sv * C57BL/6J * SJL

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+,Pdgfratm12Sor/Pdgfra+
Genetic Background: involves: 129 * 129/Sv * C57BL/6J * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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