ENSG00000105063


Homo sapiens

Features
Gene ID: ENSG00000105063
  
Biological name :PPP6R1
  
Synonyms : PPP6R1 / protein phosphatase 6 regulatory subunit 1 / Q9UPN7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.42
Gene start: 55229780
Gene end: 55258995
  
Corresponding Affymetrix probe sets: 209229_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466332
Ensembl peptide - ENSP00000467521
Ensembl peptide - ENSP00000414202
NCBI entrez gene - 22870     See in Manteia.
OMIM - 610875
RefSeq - NM_014931
RefSeq Peptide - NP_055746
swissprot - K7EM28
swissprot - Q9UPN7
Ensembl - ENSG00000105063
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Ppp6r1ENSMUSG00000052296Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPP6R3 / Q5H9R7 / protein phosphatase 6 regulatory subunit 3ENSG0000011007545
O75170 / PPP6R2 / protein phosphatase 6 regulatory subunit 2ENSG0000010023943


Protein motifs (from Interpro)
Interpro ID Name
 IPR007587  SIT4 phosphatase-associated protein family
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IDA
 biological_processGO:0048208 COPII vesicle coating TAS
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017048 Rho GTPase binding IPI
 molecular_functionGO:0019903 protein phosphatase binding IPI


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000119414 PPP6C / O00743 / protein phosphatase 6 catalytic subunit  / complex
 ENSG00000206560 O15084 / ANKRD28 / ankyrin repeat domain 28  / complex






 

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contact: otassy@igbmc.fr