ENSG00000119414


Homo sapiens

Features
Gene ID: ENSG00000119414
  
Biological name :PPP6C
  
Synonyms : O00743 / PPP6C / protein phosphatase 6 catalytic subunit
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q33.3
Gene start: 125146573
Gene end: 125189939
  
Corresponding Affymetrix probe sets: 203529_at (Human Genome U133 Plus 2.0 Array)   206174_s_at (Human Genome U133 Plus 2.0 Array)   225426_at (Human Genome U133 Plus 2.0 Array)   225429_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000416287
Ensembl peptide - ENSP00000362648
Ensembl peptide - ENSP00000392147
Ensembl peptide - ENSP00000411744
NCBI entrez gene - 5537     See in Manteia.
OMIM - 612725
RefSeq - XM_011518847
RefSeq - NM_001123355
RefSeq - NM_001123369
RefSeq - NM_002721
RefSeq Peptide - NP_001116827
RefSeq Peptide - NP_001116841
RefSeq Peptide - NP_002712
swissprot - O00743
swissprot - Q5T1S7
swissprot - A0A024R861
Ensembl - ENSG00000119414
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppp6cENSDARG00000002949Danio rerio
 PPP6CENSGALG00000001013Gallus gallus
 Ppp6cENSMUSG00000026753Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004843  Calcineurin-like phosphoesterase domain, ApaH type
 IPR006186  Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
 IPR029052  Metallo-dependent phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle TAS
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006470 protein dephosphorylation TAS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0048208 COPII vesicle coating TAS
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000110075 PPP6R3 / Q5H9R7 / protein phosphatase 6 regulatory subunit 3  / complex
 ENSG00000105063 PPP6R1 / Q9UPN7 / protein phosphatase 6 regulatory subunit 1  / complex
 ENSG00000176986 P53992 / SEC24C / SEC24 homolog C, COPII coat complex component  / reaction
 ENSG00000113615 O95486 / SEC24A / SEC24 homolog A, COPII coat complex component  / reaction
 ENSG00000206560 O15084 / ANKRD28 / ankyrin repeat domain 28  / complex
 ENSG00000138802 O95487 / SEC24B / SEC24 homolog B, COPII coat complex component  / reaction
 ENSG00000150961 O94855 / SEC24D / SEC24 homolog D, COPII coat complex component  / reaction






 

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