ENSG00000105127


Homo sapiens

Features
Gene ID: ENSG00000105127
  
Biological name :AKAP8
  
Synonyms : AKAP8 / A-kinase anchoring protein 8 / O43823
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.12
Gene start: 15353385
Gene end: 15379798
  
Corresponding Affymetrix probe sets: 203847_s_at (Human Genome U133 Plus 2.0 Array)   203848_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000269701
Ensembl peptide - ENSP00000468902
Ensembl peptide - ENSP00000469908
NCBI entrez gene - 10270     See in Manteia.
OMIM - 604692
RefSeq - XM_017026141
RefSeq - NM_005858
RefSeq - XM_011527624
RefSeq Peptide - NP_005849
swissprot - O43823
swissprot - M0QYL4
swissprot - M0QX51
Ensembl - ENSG00000105127
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Akap8ENSMUSG00000024045Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AKAP8L / Q9ULX6 / A-kinase anchoring protein 8 likeENSG0000001124328
Q5BKZ1 / ZNF326 / zinc finger protein 326ENSG0000016266421


Protein motifs (from Interpro)
Interpro ID Name
 IPR007071  A-kinase anchoring protein 95 (AKAP95)
 IPR026939  At2g23090-like
 IPR034736  Zinc finger C2H2 AKAP95-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle TAS
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007076 mitotic chromosome condensation IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0031065 positive regulation of histone deacetylation IMP
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IEA
 biological_processGO:0033127 regulation of histone phosphorylation IMP
 biological_processGO:0044839 cell cycle G2/M phase transition IMP
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071380 cellular response to prostaglandin E stimulus IEA
 cellular_componentGO:0000793 condensed chromosome IEA
 cellular_componentGO:0001939 female pronucleus IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016363 nuclear matrix IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0034237 protein kinase A regulatory subunit binding IEA
 molecular_functionGO:0042826 histone deacetylase binding IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051059 NF-kappaB binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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