ENSG00000105373


Homo sapiens

Features
Gene ID: ENSG00000105373
  
Biological name :NOP53
  
Synonyms : NOP53 / NOP53 ribosome biogenesis factor / Q9NZM5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.33
Gene start: 47745522
Gene end: 47757058
  
Corresponding Affymetrix probe sets: 217807_s_at (Human Genome U133 Plus 2.0 Array)   234339_s_at (Human Genome U133 Plus 2.0 Array)   234918_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468948
Ensembl peptide - ENSP00000470190
Ensembl peptide - ENSP00000470263
Ensembl peptide - ENSP00000470773
Ensembl peptide - ENSP00000246802
NCBI entrez gene - 29997     See in Manteia.
OMIM - 605691
RefSeq - NM_015710
RefSeq Peptide - NP_056525
swissprot - Q9NZM5
swissprot - M0QX73
swissprot - M0QYZ9
swissprot - M0QZ34
swissprot - M0QZU5
Ensembl - ENSG00000105373
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nop53ENSDARG00000100452Danio rerio
 Nop53ENSMUSG00000041560Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011687  Ribosome biogenesis protein Nop53/GLTSCR2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000027 ribosomal large subunit assembly IMP
 biological_processGO:0000055 ribosomal large subunit export from nucleus IBA
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0001932 regulation of protein phosphorylation IMP
 biological_processGO:0006281 DNA repair IMP
 biological_processGO:0006974 cellular response to DNA damage stimulus IMP
 biological_processGO:0007095 mitotic G2 DNA damage checkpoint IMP
 biological_processGO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling IMP
 biological_processGO:0031333 negative regulation of protein complex assembly IMP
 biological_processGO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0039535 regulation of RIG-I signaling pathway IMP
 biological_processGO:0042254 ribosome biogenesis IEA
 biological_processGO:0042981 regulation of apoptotic process IMP
 biological_processGO:0050821 protein stabilization IMP
 biological_processGO:0051726 regulation of cell cycle IMP
 biological_processGO:0051898 negative regulation of protein kinase B signaling IMP
 biological_processGO:0071456 cellular response to hypoxia IMP
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator IMP
 biological_processGO:1901797 negative regulation of signal transduction by p53 class mediator IEA
 biological_processGO:1901837 negative regulation of transcription of nucleolar large rRNA by RNA polymerase I IMP
 biological_processGO:1902570 protein localization to nucleolus IEA
 biological_processGO:1903006 positive regulation of protein K63-linked deubiquitination IMP
 biological_processGO:1903715 regulation of aerobic respiration IMP
 biological_processGO:1990173 protein localization to nucleoplasm IMP
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005622 intracellular NAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0033553 rDNA heterochromatin IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0002039 p53 binding IPI
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008097 5S rRNA binding IDA
 molecular_functionGO:0042802 identical protein binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr