ENSG00000105612


Homo sapiens

Features
Gene ID: ENSG00000105612
  
Biological name :DNASE2
  
Synonyms : deoxyribonuclease 2, lysosomal / DNASE2 / O00115
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.13
Gene start: 12875211
Gene end: 12881468
  
Corresponding Affymetrix probe sets: 209831_x_at (Human Genome U133 Plus 2.0 Array)   214992_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000222219
Ensembl peptide - ENSP00000466912
NCBI entrez gene - 1777     See in Manteia.
OMIM - 126350
RefSeq - NM_001375
RefSeq Peptide - NP_001366
swissprot - A0A024R7F4
swissprot - K7ENE5
swissprot - O00115
Ensembl - ENSG00000105612
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnase2ENSDARG00000073893Danio rerio
 P56542ENSMUSG00000003812Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8WZ79 / DNASE2B / deoxyribonuclease 2 betaENSG0000013797634


Protein motifs (from Interpro)
Interpro ID Name
 IPR004947  Deoxyribonuclease II


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000737 DNA catabolic process, endonucleolytic IEA
 biological_processGO:0006259 DNA metabolic process IEA
 biological_processGO:0006308 DNA catabolic process IEA
 biological_processGO:0006309 apoptotic DNA fragmentation IBA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030218 erythrocyte differentiation IEA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005764 lysosome TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0004520 endodeoxyribonuclease activity IEA
 molecular_functionGO:0004531 deoxyribonuclease II activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Lysosome Vesicle Biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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