ENSG00000137976


Homo sapiens

Features
Gene ID: ENSG00000137976
  
Biological name :DNASE2B
  
Synonyms : deoxyribonuclease 2 beta / DNASE2B / Q8WZ79
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p31.1
Gene start: 84398532
Gene end: 84415018
  
Corresponding Affymetrix probe sets: 220380_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359696
Ensembl peptide - ENSP00000359699
NCBI entrez gene - 58511     See in Manteia.
OMIM - 608057
RefSeq - XM_011541878
RefSeq - NM_021233
RefSeq - NM_058248
RefSeq Peptide - NP_490649
RefSeq Peptide - NP_067056
swissprot - Q8WZ79
Ensembl - ENSG00000137976
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnase2bENSDARG00000077918Danio rerio
 DNASE2BENSGALG00000028790Gallus gallus
 Q9QY48ENSMUSG00000028185Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DNASE2 / O00115 / deoxyribonuclease 2, lysosomalENSG0000010561234


Protein motifs (from Interpro)
Interpro ID Name
 IPR004947  Deoxyribonuclease II


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006259 DNA metabolic process IEA
 biological_processGO:0006309 apoptotic DNA fragmentation IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0004520 endodeoxyribonuclease activity IEA
 molecular_functionGO:0004531 deoxyribonuclease II activity IBA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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