ENSG00000105671


Homo sapiens

Features
Gene ID: ENSG00000105671
  
Biological name :DDX49
  
Synonyms : DDX49 / DEAD-box helicase 49 / Q9Y6V7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.11
Gene start: 18919675
Gene end: 18928633
  
Corresponding Affymetrix probe sets: 210811_s_at (Human Genome U133 Plus 2.0 Array)   232915_at (Human Genome U133 Plus 2.0 Array)   31807_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000487048
Ensembl peptide - ENSP00000247003
Ensembl peptide - ENSP00000469086
Ensembl peptide - ENSP00000470440
Ensembl peptide - ENSP00000471292
Ensembl peptide - ENSP00000472084
Ensembl peptide - ENSP00000472289
NCBI entrez gene - 54555     See in Manteia.
RefSeq - XM_011528084
RefSeq - NM_019070
RefSeq - XM_011528083
RefSeq Peptide - NP_061943
swissprot - M0R1S3
swissprot - M0QXD4
swissprot - Q9Y6V7
swissprot - M0QZC0
swissprot - M0R0K1
Ensembl - ENSG00000105671
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddx49ENSDARG00000012899Danio rerio
 DDX49ENSGALG00000003130Gallus gallus
 Ddx49ENSMUSG00000057788Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
rRNA modification in the nucleus and cytosol
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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