ENSG00000105821


Homo sapiens

Features
Gene ID: ENSG00000105821
  
Biological name :DNAJC2
  
Synonyms : DNAJC2 / DnaJ heat shock protein family (Hsp40) member C2 / Q99543
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q22.1
Gene start: 103312474
Gene end: 103344873
  
Corresponding Affymetrix probe sets: 1568884_at (Human Genome U133 Plus 2.0 Array)   213097_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000406275
Ensembl peptide - ENSP00000399058
Ensembl peptide - ENSP00000412611
Ensembl peptide - ENSP00000249270
Ensembl peptide - ENSP00000368559
Ensembl peptide - ENSP00000368565
NCBI entrez gene - 27000     See in Manteia.
OMIM - 605502
RefSeq - XM_017011968
RefSeq - NM_001129887
RefSeq - NM_014377
RefSeq - XM_005250269
RefSeq - XM_011516028
RefSeq - XM_011516029
RefSeq - XM_011516030
RefSeq Peptide - NP_055192
RefSeq Peptide - NP_001123359
swissprot - F2Z3N9
swissprot - Q99543
swissprot - C9IZ83
swissprot - H7C3L7
swissprot - F2Z3H0
Ensembl - ENSG00000105821
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnajc2ENSDARG00000070477Danio rerio
 DNAJC2ENSGALG00000008249Gallus gallus
 Dnajc2ENSMUSG00000029014Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DNAJC1 / Q96KC8 / DnaJ heat shock protein family (Hsp40) member C1ENSG0000013677020


Protein motifs (from Interpro)
Interpro ID Name
 IPR001005  SANT/Myb domain
 IPR001623  DnaJ domain
 IPR009057  Homeobox-like domain superfamily
 IPR017884  SANT domain
 IPR018253  DnaJ domain, conserved site
 IPR032003  Ribosome-associated complex head domain
 IPR036869  Chaperone J-domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0032781 positive regulation of ATPase activity IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0051083 "de novo" cotranslational protein folding TAS
 biological_processGO:1900034 regulation of cellular response to heat TAS
 biological_processGO:2000279 negative regulation of DNA biosynthetic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0031965 nuclear membrane IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0001671 ATPase activator activity TAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030544 Hsp70 protein binding IPI
 molecular_functionGO:0042393 histone binding IDA
 molecular_functionGO:0061649 ubiquitin modification-dependent histone binding IDA


Pathways (from Reactome)
Pathway description
Regulation of HSF1-mediated heat shock response


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000204389 HSPA1A / P0DMV8 / heat shock protein family A (Hsp70) member 1A  / reaction
 ENSG00000149196 Q53FT3 / HIKESHI / Hikeshi, heat shock protein nuclear import factor  / reaction
 ENSG00000204388 HSPA1B / P0DMV9 / heat shock protein family A (Hsp70) member 1B  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr