ENSG00000105849


Homo sapiens

Features
Gene ID: ENSG00000105849
  
Biological name :TWISTNB
  
Synonyms : Q3B726 / TWISTNB / TWIST neighbor
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p21.1
Gene start: 19695462
Gene end: 19709087
  
Corresponding Affymetrix probe sets: 214729_at (Human Genome U133 Plus 2.0 Array)   226784_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000222567
NCBI entrez gene - 221830     See in Manteia.
OMIM - 608312
RefSeq - NM_001002926
RefSeq Peptide - NP_001002926
swissprot - Q3B726
Ensembl - ENSG00000105849
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 twistnbENSDARG00000024416Danio rerio
 TWISTNBENSGALG00000010863Gallus gallus
 Q78WZ7ENSMUSG00000020561Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005576  RNA polymerase Rpb7, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006361 transcription initiation from RNA polymerase I promoter TAS
 biological_processGO:0006362 transcription elongation from RNA polymerase I promoter TAS
 biological_processGO:0006363 termination of RNA polymerase I transcription TAS
 biological_processGO:0045815 positive regulation of gene expression, epigenetic TAS
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005736 DNA-directed RNA polymerase I complex IBA
 molecular_functionGO:0001054 RNA polymerase I activity IBA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA


Pathways (from Reactome)
Pathway description
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase I Transcription Termination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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