ENSG00000105963


Homo sapiens

Features
Gene ID: ENSG00000105963
  
Biological name :ADAP1
  
Synonyms : ADAP1 / ArfGAP with dual PH domains 1 / O75689
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p22.3
Gene start: 897901
Gene end: 955407
  
Corresponding Affymetrix probe sets: 219150_s_at (Human Genome U133 Plus 2.0 Array)   90265_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000478011
Ensembl peptide - ENSP00000481154
Ensembl peptide - ENSP00000404217
Ensembl peptide - ENSP00000394973
Ensembl peptide - ENSP00000391315
Ensembl peptide - ENSP00000265846
Ensembl peptide - ENSP00000416545
Ensembl peptide - ENSP00000442682
Ensembl peptide - ENSP00000407267
Ensembl peptide - ENSP00000409129
Ensembl peptide - ENSP00000414436
NCBI entrez gene - 11033     See in Manteia.
OMIM - 608114
RefSeq - NM_001284310
RefSeq - NM_006869
RefSeq - NM_001284308
RefSeq - NM_001284309
RefSeq - NM_001284311
RefSeq Peptide - NP_001271238
RefSeq Peptide - NP_001271237
RefSeq Peptide - NP_006860
RefSeq Peptide - NP_001271240
RefSeq Peptide - NP_001271239
swissprot - O75689
swissprot - A0A087WTN6
swissprot - C9JN36
swissprot - H0Y7Q1
swissprot - H7BZT6
swissprot - H7C264
swissprot - H7C324
swissprot - H7C4B3
Ensembl - ENSG00000105963
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:92360ENSDARG00000038151Danio rerio
 ADAP1ENSGALG00000003819Gallus gallus
 Adap1ENSMUSG00000056413Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADAP2 / Q9NPF8 / ArfGAP with dual PH domains 2ENSG0000018406054
SMAP2 / Q8WU79 / small ArfGAP2ENSG0000008407021
SMAP1 / Q8IYB5 / small ArfGAP 1ENSG0000011230520


Protein motifs (from Interpro)
Interpro ID Name
 IPR001164  Arf GTPase activating protein
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR037278  ARFGAP/RecO-like zinc finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0043087 regulation of GTPase activity IMP
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IEA
 molecular_functionGO:0043533 inositol 1,3,4,5 tetrakisphosphate binding TAS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:1902936 phosphatidylinositol bisphosphate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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