ENSG00000184060


Homo sapiens

Features
Gene ID: ENSG00000184060
  
Biological name :ADAP2
  
Synonyms : ADAP2 / ArfGAP with dual PH domains 2 / Q9NPF8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q11.2
Gene start: 30906344
Gene end: 30959322
  
Corresponding Affymetrix probe sets: 219358_s_at (Human Genome U133 Plus 2.0 Array)   222876_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464120
Ensembl peptide - ENSP00000464121
Ensembl peptide - ENSP00000464155
Ensembl peptide - ENSP00000467079
Ensembl peptide - ENSP00000329468
Ensembl peptide - ENSP00000462634
Ensembl peptide - ENSP00000462832
Ensembl peptide - ENSP00000463649
NCBI entrez gene - 55803     See in Manteia.
OMIM - 608635
RefSeq - NM_018404
RefSeq - NM_001346712
RefSeq - NM_001346714
RefSeq Peptide - NP_001333641
RefSeq Peptide - NP_001333643
RefSeq Peptide - NP_060874
swissprot - Q9NPF8
swissprot - J3KST1
swissprot - J3KT70
swissprot - J3QLP8
swissprot - J3QRA6
swissprot - J3QRD3
swissprot - K7ENT1
swissprot - Q2V6Q1
Ensembl - ENSG00000184060
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adap2ENSDARG00000070565Danio rerio
 ADAP2ENSGALG00000003319Gallus gallus
 Adap2ENSMUSG00000020709Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADAP1 / O75689 / ArfGAP with dual PH domains 1ENSG0000010596354
SMAP1 / Q8IYB5 / small ArfGAP 1ENSG0000011230523
SMAP2 / Q8WU79 / small ArfGAP2ENSG0000008407021


Protein motifs (from Interpro)
Interpro ID Name
 IPR001164  Arf GTPase activating protein
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR037278  ARFGAP/RecO-like zinc finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007507 heart development IEP
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005740 mitochondrial envelope ISS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding ISS
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IDA
 molecular_functionGO:0030674 protein binding, bridging NAS
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding ISS
 molecular_functionGO:0043533 inositol 1,3,4,5 tetrakisphosphate binding IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:1902936 phosphatidylinositol bisphosphate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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