ENSMUSG00000020709


Mus musculus

Features
Gene ID: ENSMUSG00000020709
  
Biological name :Adap2
  
Synonyms : Adap2 / Arf-GAP with dual PH domain-containing protein 2 / Q8R2V5
  
Possible biological names infered from orthology : ArfGAP with dual PH domains 2 / Q9NPF8
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B5
Gene start: 80154105
Gene end: 80178958
  
Corresponding Affymetrix probe sets: 10379389 (MoGene1.0st)   1425638_at (Mouse Genome 430 2.0 Array)   1425639_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021050
Ensembl peptide - ENSMUSP00000130731
NCBI entrez gene - 216991     See in Manteia.
MGI - MGI:2663075
RefSeq - XM_006532973
RefSeq - NM_172133
RefSeq Peptide - NP_742145
swissprot - Q5SSK2
swissprot - Q8R2V5
swissprot - E9QAL8
Ensembl - ENSMUSG00000020709
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adap2ENSDARG00000070565Danio rerio
 ADAP2ENSGALG00000003319Gallus gallus
 ADAP2ENSG00000184060Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Adap1 / ArfGAP with dual PH domains 1 / O75689*ENSMUSG0000005641355
Smap1 / Q91VZ6 / small ArfGAP 1 / Q8IYB5*ENSMUSG0000002615522
Smap2 / Q7TN29 / small ArfGAP 2 / Q8WU79*ENSMUSG0000003287019


Protein motifs (from Interpro)
Interpro ID Name
 IPR001164  Arf GTPase activating protein
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR037278  ARFGAP/RecO-like zinc finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007507 heart development IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0048017 inositol lipid-mediated signaling ISO
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005740 mitochondrial envelope ISS
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding ISS
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IEA
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding ISS
 molecular_functionGO:0043533 inositol 1,3,4,5 tetrakisphosphate binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:1902936 phosphatidylinositol bisphosphate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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