ENSDARG00000070565


Danio rerio

Features
Gene ID: ENSDARG00000070565
  
Biological name :adap2
  
Synonyms : adap2 / ArfGAP with dual PH domains 2
  
Possible biological names infered from orthology : Arf-GAP with dual PH domain-containing protein 2 / Q8R2V5 / Q9NPF8
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 26267725
Gene end: 26281561
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000119626
NCBI entrez gene - 100331455     See in Manteia.
swissprot - E9QE78
ZFIN ID - ZDB-GENE-070912-21
Ensembl - ENSDARG00000070565
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADAP2ENSGALG00000003319Gallus gallus
 ADAP2ENSG00000184060Homo sapiens
 Adap2ENSMUSG00000020709Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zgc:92360 / ADAP1* / O75689* / ArfGAP with dual PH domains 1*ENSDARG0000003815152
smap1 / small ArfGAP 1 / Q8IYB5* / Q91VZ6*ENSDARG0000003130223
smap2 / small ArfGAP2 / Q7TN29* / Q8WU79*ENSDARG0000006144620


Protein motifs (from Interpro)
Interpro ID Name
 IPR001164  Arf GTPase activating protein
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0003146 heart jogging IMP
 biological_processGO:0003171 atrioventricular valve development IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:1902936 phosphatidylinositol bisphosphate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood accumulation head , abnormal
blood accumulation trunk , abnormal
blood accumulation post-vent region , abnormal
Show

 ZFA:0000009 cardiac ventricle cardiac ventricle decreased size , abnormal
Show

 ZFA:0000114 heart heart morphology , abnormal
Show

 ZFA:0001117 post-vent region post-vent region increased curvature , abnormal
post-vent region bent , abnormal
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 ZFA:0001315 atrioventricular canal atrioventricular canal shape , abnormal
Show

 ZFA:0001317 endocardial cushion endocardial cushion morphology , abnormal
Show

 ZFA:0005064 atrioventricular valve atrioventricular valve morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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