ENSG00000105971


Homo sapiens

Features
Gene ID: ENSG00000105971
  
Biological name :CAV2
  
Synonyms : CAV2 / caveolin 2 / P51636
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q31.2
Gene start: 116287380
Gene end: 116508541
  
Corresponding Affymetrix probe sets: 203323_at (Human Genome U133 Plus 2.0 Array)   203324_s_at (Human Genome U133 Plus 2.0 Array)   213426_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000377120
Ensembl peptide - ENSP00000222693
Ensembl peptide - ENSP00000345679
NCBI entrez gene - 858     See in Manteia.
OMIM - 601048
RefSeq - NM_001233
RefSeq - NM_001206747
RefSeq - NM_198212
RefSeq Peptide - NP_001193676
RefSeq Peptide - NP_001224
RefSeq Peptide - NP_937855
swissprot - Q53X57
swissprot - P51636
swissprot - E9PCT3
Ensembl - ENSG00000105971
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cav2ENSDARG00000052000Danio rerio
 CAV2ENSGALG00000033295Gallus gallus
 Cav2ENSMUSG00000000058Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CAV1 / Q03135 / caveolin 1ENSG0000010597435
CAV3 / P56539 / caveolin 3ENSG0000018253332


Protein motifs (from Interpro)
Interpro ID Name
 IPR001612  Caveolin
 IPR018361  Caveolin, conserved site
 IPR033306  Caveolin-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001937 negative regulation of endothelial cell proliferation ISS
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IEA
 biological_processGO:0006906 vesicle fusion IDA
 biological_processGO:0007005 mitochondrion organization ISS
 biological_processGO:0007029 endoplasmic reticulum organization ISS
 biological_processGO:0007088 regulation of mitotic nuclear division IEP
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0008286 insulin receptor signaling pathway IDA
 biological_processGO:0016050 vesicle organization IDA
 biological_processGO:0019065 receptor-mediated endocytosis of virus by host cell IGI
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IDA
 biological_processGO:0043547 positive regulation of GTPase activity IDA
 biological_processGO:0044791 positive regulation by host of viral release from host cell IMP
 biological_processGO:0044794 positive regulation by host of viral process IMP
 biological_processGO:0048278 vesicle docking IDA
 biological_processGO:0048741 skeletal muscle fiber development ISS
 biological_processGO:0051259 protein complex oligomerization IEA
 biological_processGO:0060161 positive regulation of dopamine receptor signaling pathway IMP
 biological_processGO:0070836 caveola assembly IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0002080 acrosomal membrane IEA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0005901 caveola IEA
 cellular_componentGO:0005925 focal adhesion IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030133 transport vesicle IDA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0045121 membrane raft IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0030674 protein binding, bridging IEA
 molecular_functionGO:0032947 protein-containing complex scaffold activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0097110 scaffold protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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