ENSG00000106268


Homo sapiens

Features
Gene ID: ENSG00000106268
  
Biological name :NUDT1
  
Synonyms : nudix hydrolase 1 / NUDT1 / P36639
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p22.3
Gene start: 2242222
Gene end: 2251146
  
Corresponding Affymetrix probe sets: 204766_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000380239
Ensembl peptide - ENSP00000349148
Ensembl peptide - ENSP00000380241
Ensembl peptide - ENSP00000405334
Ensembl peptide - ENSP00000380242
Ensembl peptide - ENSP00000339503
Ensembl peptide - ENSP00000343439
NCBI entrez gene - 4521     See in Manteia.
OMIM - 600312
RefSeq - NM_198948
RefSeq - NM_002452
RefSeq - NM_198949
RefSeq - NM_198950
RefSeq - NM_198952
RefSeq - NM_198953
RefSeq - NM_198954
RefSeq Peptide - NP_945191
RefSeq Peptide - NP_945192
RefSeq Peptide - NP_945186
RefSeq Peptide - NP_945187
RefSeq Peptide - NP_945188
RefSeq Peptide - NP_945190
RefSeq Peptide - NP_002443
swissprot - P36639
swissprot - A0A024R858
swissprot - A0A024R819
swissprot - C9J361
Ensembl - ENSG00000106268
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nudt1ENSDARG00000030573Danio rerio
 NUDT1ENSGALG00000004245Gallus gallus
 Nudt1ENSMUSG00000036639Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000086  NUDIX hydrolase domain
 IPR003563  7,8-dihydro-8-oxoguanine triphosphatase
 IPR015797  NUDIX hydrolase-like domain superfamily
 IPR020084  NUDIX hydrolase, conserved site
 IPR020476  NUDIX hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006195 purine nucleotide catabolic process IDA
 biological_processGO:0006203 dGTP catabolic process IDA
 biological_processGO:0006281 DNA repair IC
 biological_processGO:0006979 response to oxidative stress TAS
 biological_processGO:0007568 aging IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0034656 nucleobase-containing small molecule catabolic process TAS
 biological_processGO:0042262 DNA protection IDA
 biological_processGO:0046061 dATP catabolic process IDA
 biological_processGO:0046686 response to cadmium ion IEA
 cellular_componentGO:0001669 acrosomal vesicle IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003924 GTPase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030515 snoRNA binding ISS
 molecular_functionGO:0035539 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity EXP
 molecular_functionGO:0036219 GTP diphosphatase activity IDA
 molecular_functionGO:0044713 2-hydroxy-adenosine triphosphate pyrophosphatase activity EXP
 molecular_functionGO:0044714 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity EXP
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047693 ATP diphosphatase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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