ENSG00000106853


Homo sapiens

Features
Gene ID: ENSG00000106853
  
Biological name :PTGR1
  
Synonyms : prostaglandin reductase 1 / PTGR1 / Q14914
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q31.3
Gene start: 111549722
Gene end: 111599855
  
Corresponding Affymetrix probe sets: 228824_s_at (Human Genome U133 Plus 2.0 Array)   228825_at (Human Genome U133 Plus 2.0 Array)   231897_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000440281
Ensembl peptide - ENSP00000395965
Ensembl peptide - ENSP00000435665
Ensembl peptide - ENSP00000311572
Ensembl peptide - ENSP00000363444
Ensembl peptide - ENSP00000385763
NCBI entrez gene - 22949     See in Manteia.
OMIM - 601274
RefSeq - XM_017014485
RefSeq - NM_001146108
RefSeq - NM_001146109
RefSeq - NM_012212
RefSeq - XM_011518394
RefSeq Peptide - NP_001139580
RefSeq Peptide - NP_001139581
RefSeq Peptide - NP_036344
swissprot - F6XGT7
swissprot - Q14914
swissprot - Q5JVP2
swissprot - F2Z3J9
Ensembl - ENSG00000106853
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptgr1ENSDARG00000024877Danio rerio
 si:dkey-11k2.7ENSDARG00000087017Danio rerio
 PTGR1ENSGALG00000015702Gallus gallus
 Ptgr1ENSMUSG00000028378Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTGR2 / Q8N8N7 / prostaglandin reductase 2ENSG0000014004339
AC005520.1ENSG0000025865329


Protein motifs (from Interpro)
Interpro ID Name
 IPR011032  GroES-like superfamily
 IPR013149  Alcohol dehydrogenase, C-terminal
 IPR014190  Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase
 IPR020843  Polyketide synthase, enoylreductase domain
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006691 leukotriene metabolic process NAS
 biological_processGO:0006693 prostaglandin metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0097327 response to antineoplastic agent IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0032440 2-alkenal reductase [NAD(P)] activity IEA
 molecular_functionGO:0036132 13-prostaglandin reductase activity IEA
 molecular_functionGO:0047522 15-oxoprostaglandin 13-oxidase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of Leukotrienes (LT) and Eoxins (EX)
Synthesis of Lipoxins (LX)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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