ENSG00000140043


Homo sapiens

Features
Gene ID: ENSG00000140043
  
Biological name :PTGR2
  
Synonyms : prostaglandin reductase 2 / PTGR2 / Q8N8N7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q24.3
Gene start: 73851844
Gene end: 73886827
  
Corresponding Affymetrix probe sets: 230774_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000267568
Ensembl peptide - ENSP00000450824
Ensembl peptide - ENSP00000450975
Ensembl peptide - ENSP00000452280
NCBI entrez gene - 145482     See in Manteia.
OMIM - 608642
RefSeq - NM_001146154
RefSeq - NM_001146155
RefSeq - NM_152444
RefSeq Peptide - NP_001139626
RefSeq Peptide - NP_001139627
RefSeq Peptide - NP_689657
swissprot - V9HW32
swissprot - G3V2R9
swissprot - Q8N8N7
Ensembl - ENSG00000140043
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptgr2ENSDARG00000070673Danio rerio
 PTGR2ENSGALG00000009269Gallus gallus
 Ptgr2ENSMUSG00000072946Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC005520.1ENSG0000025865377
PTGR1 / Q14914 / prostaglandin reductase 1ENSG0000010685337


Protein motifs (from Interpro)
Interpro ID Name
 IPR011032  GroES-like superfamily
 IPR013149  Alcohol dehydrogenase, C-terminal
 IPR036291  NAD(P)-binding domain superfamily
 IPR037399  Prostaglandin reductase 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006693 prostaglandin metabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0036132 13-prostaglandin reductase activity IEA
 molecular_functionGO:0047522 15-oxoprostaglandin 13-oxidase activity IDA


Pathways (from Reactome)
Pathway description
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr