ENSG00000107679


Homo sapiens

Features
Gene ID: ENSG00000107679
  
Biological name :PLEKHA1
  
Synonyms : pleckstrin homology domain containing A1 / PLEKHA1 / Q9HB21
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q26.13
Gene start: 122374696
Gene end: 122442602
  
Corresponding Affymetrix probe sets: 219024_at (Human Genome U133 Plus 2.0 Array)   226247_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000394416
Ensembl peptide - ENSP00000357984
Ensembl peptide - ENSP00000357985
Ensembl peptide - ENSP00000357986
Ensembl peptide - ENSP00000473424
Ensembl peptide - ENSP00000376547
NCBI entrez gene - 59338     See in Manteia.
OMIM - 607772
RefSeq - XM_017016491
RefSeq - NM_001001974
RefSeq - NM_001195608
RefSeq - NM_001330178
RefSeq - NM_021622
RefSeq - XM_017016484
RefSeq - XM_017016485
RefSeq - XM_017016486
RefSeq - XM_017016487
RefSeq - XM_017016488
RefSeq - XM_017016489
RefSeq - XM_017016490
RefSeq - XM_005270016
RefSeq - XM_005270019
RefSeq - XM_005270020
RefSeq - XM_005270021
RefSeq - XM_011540017
RefSeq - XM_011540018
RefSeq - XM_011540019
RefSeq - XM_011540021
RefSeq - XM_011540022
RefSeq - XM_011540024
RefSeq - XM_017016478
RefSeq - XM_017016479
RefSeq - XM_017016480
RefSeq - XM_017016481
RefSeq - XM_017016482
RefSeq - XM_017016483
RefSeq Peptide - NP_001317107
RefSeq Peptide - NP_067635
RefSeq Peptide - NP_001001974
RefSeq Peptide - NP_001182537
swissprot - Q5RGS4
swissprot - Q9HB21
swissprot - R4GMZ9
Ensembl - ENSG00000107679
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLEKHA1ENSGALG00000034548Gallus gallus
 Q8BUL6ENSMUSG00000040268Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PLEKHA2 / pleckstrin homology domain containing A2ENSG0000016949945


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001553 luteinization IEA
 biological_processGO:0006661 phosphatidylinositol biosynthetic process TAS
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0008209 androgen metabolic process IEA
 biological_processGO:0008210 estrogen metabolic process IEA
 biological_processGO:0008585 female gonad development IEA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0014065 phosphatidylinositol 3-kinase signaling IDA
 biological_processGO:0031529 ruffle organization IDA
 biological_processGO:0033327 Leydig cell differentiation IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0045184 establishment of protein localization IDA
 biological_processGO:0048008 platelet-derived growth factor receptor signaling pathway IEA
 biological_processGO:0048705 skeletal system morphogenesis IEA
 biological_processGO:0050853 B cell receptor signaling pathway IDA
 biological_processGO:0051898 negative regulation of protein kinase B signaling IMP
 biological_processGO:0060021 roof of mouth development IEA
 biological_processGO:0060325 face morphogenesis IEA
 biological_processGO:0070301 cellular response to hydrogen peroxide IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032587 ruffle membrane IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0030165 PDZ domain binding IPI
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding IDA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000163629 PTPN13 / Q12923 / protein tyrosine phosphatase, non-receptor type 13  / complex






 

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