ENSG00000107829


Homo sapiens

Features
Gene ID: ENSG00000107829
  
Biological name :FBXW4
  
Synonyms : F-box and WD repeat domain containing 4 / FBXW4 / P57775
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q24.32
Gene start: 101610664
Gene end: 101695295
  
Corresponding Affymetrix probe sets: 221519_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359149
NCBI entrez gene - 6468     See in Manteia.
OMIM - 608071
RefSeq - XM_005270053
RefSeq - NM_001323541
RefSeq - NM_022039
RefSeq Peptide - NP_071322
RefSeq Peptide - NP_001310470
swissprot - P57775
Ensembl - ENSG00000107829
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxw4ENSDARG00000033551Danio rerio
 FBXW4ENSGALG00000043428Gallus gallus
 Fbxw4ENSMUSG00000040913Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR001810  F-box domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR036047  F-box-like domain superfamily
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process NAS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030326 embryonic limb morphogenesis NAS
 biological_processGO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0042733 embryonic digit morphogenesis IEA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0051216 cartilage development IEA
 biological_processGO:0060173 limb development IEA
 cellular_componentGO:0000151 ubiquitin ligase complex NAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IBA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Association of TriC/CCT with target proteins during biosynthesis
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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