ENSG00000107902


Homo sapiens

Features
Gene ID: ENSG00000107902
  
Biological name :LHPP
  
Synonyms : LHPP / phospholysine phosphohistidine inorganic pyrophosphate phosphatase / Q9H008
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q26.13
Gene start: 124461834
Gene end: 124617888
  
Corresponding Affymetrix probe sets: 218523_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357832
Ensembl peptide - ENSP00000357835
Ensembl peptide - ENSP00000376512
NCBI entrez gene - 64077     See in Manteia.
OMIM - 617231
RefSeq - XM_017016511
RefSeq - NM_001167880
RefSeq - NM_001318331
RefSeq - NM_001318332
RefSeq - NM_022126
RefSeq - XM_005270026
RefSeq - XM_006717943
RefSeq - XM_011540058
RefSeq - XM_017016510
RefSeq Peptide - NP_001161352
RefSeq Peptide - NP_001305260
RefSeq Peptide - NP_001305261
RefSeq Peptide - NP_071409
swissprot - Q9H008
swissprot - Q5T1Z0
Ensembl - ENSG00000107902
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lhppENSDARG00000060196Danio rerio
 LHPPENSGALG00000030925Gallus gallus
 LhppENSMUSG00000030946Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HDHD2 / Q9H0R4 / haloacid dehalogenase like hydrolase domain containing 2ENSG0000016722041


Protein motifs (from Interpro)
Interpro ID Name
 IPR006355  HAD hydrolase, LHPP/HDHD2
 IPR006357  HAD-superfamily hydrolase, subfamily IIA
 IPR023214  HAD superfamily
 IPR036412  HAD-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation ISS
 biological_processGO:0006796 phosphate-containing compound metabolic process IDA
 biological_processGO:0009168 purine ribonucleoside monophosphate biosynthetic process TAS
 biological_processGO:0016311 dephosphorylation IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0000287 magnesium ion binding ISS
 molecular_functionGO:0004427 inorganic diphosphatase activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IBA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0101006 protein histidine phosphatase activity ISS


Pathways (from Reactome)
Pathway description
Purine ribonucleoside monophosphate biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000107902 LHPP / Q9H008 / phospholysine phosphohistidine inorganic pyrophosphate phosphatase  / complex






 

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