ENSG00000107937


Homo sapiens

Features
Gene ID: ENSG00000107937
  
Biological name :GTPBP4
  
Synonyms : GTP binding protein 4 / GTPBP4 / Q9BZE4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: p15.3
Gene start: 988019
Gene end: 1019936
  
Corresponding Affymetrix probe sets: 217631_at (Human Genome U133 Plus 2.0 Array)   218238_at (Human Genome U133 Plus 2.0 Array)   218239_s_at (Human Genome U133 Plus 2.0 Array)   228002_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000354040
Ensembl peptide - ENSP00000353168
NCBI entrez gene - 23560     See in Manteia.
RefSeq - NM_012341
RefSeq Peptide - NP_036473
swissprot - D2CFK9
swissprot - Q5T3R7
swissprot - Q9BZE4
Ensembl - ENSG00000107937
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gtpbp4ENSDARG00000018961Danio rerio
 GTPBP4ENSGALG00000006703Gallus gallus
 Gtpbp4ENSMUSG00000021149Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005225  Small GTP-binding protein domain
 IPR006073  GTP binding domain
 IPR010674  Nucleolar GTP-binding protein 1, Rossman-fold domain
 IPR012973  NOG, C-terminal
 IPR024926  Nucleolar GTP-binding protein 1
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031167  OBG-type guanine nucleotide-binding (G) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity IDA
 biological_processGO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IEA
 biological_processGO:0001649 osteoblast differentiation HDA
 biological_processGO:0008156 negative regulation of DNA replication IMP
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0022408 negative regulation of cell-cell adhesion IDA
 biological_processGO:0030336 negative regulation of cell migration IDA
 biological_processGO:0031397 negative regulation of protein ubiquitination IDA
 biological_processGO:0033342 negative regulation of collagen binding IMP
 biological_processGO:0042254 ribosome biogenesis IEA
 biological_processGO:0050821 protein stabilization IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0031965 nuclear membrane IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003924 GTPase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr