ENSG00000107959


Homo sapiens

Features
Gene ID: ENSG00000107959
  
Biological name :PITRM1
  
Synonyms : pitrilysin metallopeptidase 1 / PITRM1 / Q5JRX3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: p15.2
Gene start: 3137728
Gene end: 3172841
  
Corresponding Affymetrix probe sets: 205273_s_at (Human Genome U133 Plus 2.0 Array)   239378_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000399307
Ensembl peptide - ENSP00000401201
Ensembl peptide - ENSP00000413687
Ensembl peptide - ENSP00000402072
Ensembl peptide - ENSP00000224949
Ensembl peptide - ENSP00000370377
Ensembl peptide - ENSP00000370382
Ensembl peptide - ENSP00000391526
NCBI entrez gene - 10531     See in Manteia.
RefSeq - XM_017015473
RefSeq - NM_001242307
RefSeq - NM_001242309
RefSeq - NM_001347725
RefSeq - NM_001347728
RefSeq - NM_014889
RefSeq - XM_005252345
RefSeq - XM_017015470
RefSeq - XM_017015471
RefSeq - XM_017015472
RefSeq Peptide - NP_001334654
RefSeq Peptide - NP_001334657
RefSeq Peptide - NP_055704
RefSeq Peptide - NP_001229238
RefSeq Peptide - NP_001229236
swissprot - Q5JRX3
swissprot - A0A0A0MRX9
swissprot - B1APQ1
swissprot - B1APQ0
swissprot - H0Y4F7
swissprot - H0Y7L7
Ensembl - ENSG00000107959
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pitrm1ENSDARG00000038563Danio rerio
 PITRM1ENSGALG00000007036Gallus gallus
 Pitrm1ENSMUSG00000021193Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007863  Peptidase M16, C-terminal
 IPR011249  Metalloenzyme, LuxS/M16 peptidase-like
 IPR011765  Peptidase M16, N-terminal
 IPR013578  Peptidase M16C associated


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IMP
 biological_processGO:0006626 protein targeting to mitochondrion TAS
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IMP
 molecular_functionGO:0008047 enzyme activator activity TAS
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity EXP
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Mitochondrial protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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