ENSG00000108010


Homo sapiens

Features
Gene ID: ENSG00000108010
  
Biological name :GLRX3
  
Synonyms : GLRX3 / glutaredoxin 3 / O76003
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q26.3
Gene start: 130136399
Gene end: 130184521
  
Corresponding Affymetrix probe sets: 207506_at (Human Genome U133 Plus 2.0 Array)   209080_x_at (Human Genome U133 Plus 2.0 Array)   214205_x_at (Human Genome U133 Plus 2.0 Array)   230095_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000435445
Ensembl peptide - ENSP00000330836
Ensembl peptide - ENSP00000357633
NCBI entrez gene - 10539     See in Manteia.
OMIM - 612754
RefSeq - XM_017015474
RefSeq - NM_001199868
RefSeq - NM_001321980
RefSeq - NM_006541
RefSeq Peptide - NP_001186797
RefSeq Peptide - NP_001308909
RefSeq Peptide - NP_006532
swissprot - O76003
swissprot - A0A140VJK1
Ensembl - ENSG00000108010
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 glrx3ENSDARG00000098785Danio rerio
 GLRX3ENSGALG00000010464Gallus gallus
 Glrx3ENSMUSG00000031068Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002109  Glutaredoxin
 IPR004480  Monothiol glutaredoxin-related
 IPR013766  Thioredoxin domain
 IPR033658  Glutaredoxin, PICOT-like
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002026 regulation of the force of heart contraction ISS
 biological_processGO:0010614 negative regulation of cardiac muscle hypertrophy ISS
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0044571 [2Fe-2S] cluster assembly IDA
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0097428 protein maturation by iron-sulfur cluster transfer IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005080 protein kinase C binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0009055 electron transfer activity IEA
 molecular_functionGO:0015035 protein disulfide oxidoreductase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Iron uptake and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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