ENSG00000108465


Homo sapiens

Features
Gene ID: ENSG00000108465
  
Biological name :CDK5RAP3
  
Synonyms : CDK5RAP3 / CDK5 regulatory subunit associated protein 3 / Q96JB5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q21.32
Gene start: 47967810
Gene end: 47981774
  
Corresponding Affymetrix probe sets: 218740_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464542
Ensembl peptide - ENSP00000464286
Ensembl peptide - ENSP00000464419
Ensembl peptide - ENSP00000344683
Ensembl peptide - ENSP00000438886
Ensembl peptide - ENSP00000462012
Ensembl peptide - ENSP00000462042
Ensembl peptide - ENSP00000462328
Ensembl peptide - ENSP00000462431
Ensembl peptide - ENSP00000462886
Ensembl peptide - ENSP00000463431
Ensembl peptide - ENSP00000463442
Ensembl peptide - ENSP00000463878
Ensembl peptide - ENSP00000463950
NCBI entrez gene - 80279     See in Manteia.
OMIM - 608202
RefSeq - NM_176096
RefSeq - NM_001278197
RefSeq - NM_001278198
RefSeq - NM_001278216
RefSeq - NM_001278217
RefSeq - XM_011525297
RefSeq - XM_017025164
RefSeq - XM_017025165
RefSeq - XM_017025166
RefSeq Peptide - NP_001265126
RefSeq Peptide - NP_001265127
RefSeq Peptide - NP_788276
RefSeq Peptide - NP_001265145
RefSeq Peptide - NP_001265146
swissprot - J3KRK4
swissprot - J3KS63
swissprot - J3KSD0
swissprot - J3KTA5
swissprot - J3QL86
swissprot - J3QL95
swissprot - J3QQS7
swissprot - J3QRM1
swissprot - J3QQY1
swissprot - J3QRX0
swissprot - J3QS62
swissprot - Q96JB5
swissprot - J3KRI2
Ensembl - ENSG00000108465
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdk5rap3ENSDARG00000045092Danio rerio
 CDK5RAP3ENSGALG00000036452Gallus gallus
 Q99LM2ENSMUSG00000018669Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008491  CDK5 regulatory subunit-associated protein 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity IBA
 biological_processGO:0001933 negative regulation of protein phosphorylation IMP
 biological_processGO:0007095 mitotic G2 DNA damage checkpoint IMP
 biological_processGO:0007420 brain development NAS
 biological_processGO:0008283 cell proliferation IDA
 biological_processGO:0010921 regulation of phosphatase activity IMP
 biological_processGO:0030262 apoptotic nuclear changes IMP
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IMP
 biological_processGO:0031398 positive regulation of protein ubiquitination IDA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IMP
 biological_processGO:0043407 negative regulation of MAP kinase activity IMP
 biological_processGO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation IMP
 biological_processGO:0044818 mitotic G2/M transition checkpoint IMP
 biological_processGO:0045664 regulation of neuron differentiation NAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0071569 protein ufmylation IDA
 biological_processGO:0071901 negative regulation of protein serine/threonine kinase activity IMP
 biological_processGO:1900182 positive regulation of protein localization to nucleus IDA
 biological_processGO:1901798 positive regulation of signal transduction by p53 class mediator IDA
 biological_processGO:1903363 negative regulation of cellular protein catabolic process IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IDA
 cellular_componentGO:0012505 endomembrane system IBA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding NAS
 molecular_functionGO:0030332 cyclin binding IPI
 molecular_functionGO:0044389 ubiquitin-like protein ligase binding IDA
 molecular_functionGO:0051019 mitogen-activated protein kinase binding IPI
 molecular_functionGO:0051059 NF-kappaB binding IPI
 molecular_functionGO:0097371 MDM2/MDM4 family protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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