ENSMUSG00000018669


Mus musculus

Features
Gene ID: ENSMUSG00000018669
  
Biological name :Cdk5rap3
  
Synonyms : Cdk5rap3 / CDK5 regulatory subunit-associated protein 3 / Q99LM2
  
Possible biological names infered from orthology : Q96JB5
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: D
Gene start: 96907426
Gene end: 96916496
  
Corresponding Affymetrix probe sets: 10390283 (MoGene1.0st)   1423067_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114661
Ensembl peptide - ENSMUSP00000123113
Ensembl peptide - ENSMUSP00000120258
Ensembl peptide - ENSMUSP00000118320
Ensembl peptide - ENSMUSP00000116405
Ensembl peptide - ENSMUSP00000114849
Ensembl peptide - ENSMUSP00000114724
Ensembl peptide - ENSMUSP00000099441
NCBI entrez gene - 80280     See in Manteia.
MGI - MGI:1933126
RefSeq - XM_011249320
RefSeq - NM_001308183
RefSeq - NM_030248
RefSeq - XM_006534526
RefSeq - XM_011249319
RefSeq Peptide - NP_001295112
RefSeq Peptide - NP_084524
swissprot - Q99LM2
swissprot - D6RJ46
swissprot - B0QZI8
swissprot - A2A6E1
swissprot - A2A6E0
swissprot - F2Z486
swissprot - A2A6D9
swissprot - D6RII4
Ensembl - ENSMUSG00000018669
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdk5rap3ENSDARG00000045092Danio rerio
 CDK5RAP3ENSGALG00000036452Gallus gallus
 Q96JB5ENSG00000108465Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008491  CDK5 regulatory subunit-associated protein 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity ISS
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0007095 mitotic G2 DNA damage checkpoint IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0010921 regulation of phosphatase activity IEA
 biological_processGO:0030262 apoptotic nuclear changes IEA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IEA
 biological_processGO:0031398 positive regulation of protein ubiquitination IEA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0043407 negative regulation of MAP kinase activity IEA
 biological_processGO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation IEA
 biological_processGO:0044818 mitotic G2/M transition checkpoint IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IGI
 biological_processGO:0071569 protein ufmylation IEA
 biological_processGO:0071901 negative regulation of protein serine/threonine kinase activity IEA
 biological_processGO:1900182 positive regulation of protein localization to nucleus IEA
 biological_processGO:1901798 positive regulation of signal transduction by p53 class mediator IEA
 biological_processGO:1903363 negative regulation of cellular protein catabolic process IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0012505 endomembrane system IBA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0030332 cyclin binding IEA
 molecular_functionGO:0044389 ubiquitin-like protein ligase binding IEA
 molecular_functionGO:0051019 mitogen-activated protein kinase binding IEA
 molecular_functionGO:0051059 NF-kappaB binding IEA
 molecular_functionGO:0097371 MDM2/MDM4 family protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Cdk4tm1b(NCOM)Mfgc/Cdk4tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Cdk4tm1b(NCOM)Mfgc/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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