ENSG00000108924


Homo sapiens

Features
Gene ID: ENSG00000108924
  
Biological name :HLF
  
Synonyms : HLF / HLF, PAR bZIP transcription factor / Q16534
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q22
Gene start: 55265012
Gene end: 55325065
  
Corresponding Affymetrix probe sets: 204753_s_at (Human Genome U133 Plus 2.0 Array)   204754_at (Human Genome U133 Plus 2.0 Array)   204755_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000461455
Ensembl peptide - ENSP00000460296
Ensembl peptide - ENSP00000460572
Ensembl peptide - ENSP00000226067
Ensembl peptide - ENSP00000402496
Ensembl peptide - ENSP00000460265
NCBI entrez gene - 3131     See in Manteia.
OMIM - 142385
RefSeq - XM_017024556
RefSeq - NM_002126
RefSeq - XM_005257269
RefSeq - XM_011524705
RefSeq Peptide - NP_002117
RefSeq Peptide - NP_001317304
swissprot - Q16534
swissprot - I3L4R4
swissprot - I3L386
Ensembl - ENSG00000108924
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hlfaENSDARG00000074752Danio rerio
 hlfbENSDARG00000061011Danio rerio
 HLFENSGALG00000003059Gallus gallus
 HlfENSMUSG00000003949Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TEF / Q10587 / TEF, PAR bZIP transcription factorENSG0000016707452
DBP / Q10586 / D-box binding PAR bZIP transcription factorENSG0000010551644


Protein motifs (from Interpro)
Interpro ID Name
 IPR004827  Basic-leucine zipper domain
 IPR029829  Hepatic leukemia factor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0035914 skeletal muscle cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0048511 rhythmic process IEA
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding TAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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