ENSG00000108961


Homo sapiens

Features
Gene ID: ENSG00000108961
  
Biological name :RANGRF
  
Synonyms : Q9HD47 / RANGRF / RAN guanine nucleotide release factor
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: p13.1
Gene start: 8288497
Gene end: 8290092
  
Corresponding Affymetrix probe sets: 218526_s_at (Human Genome U133 Plus 2.0 Array)   223554_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000226105
Ensembl peptide - ENSP00000383940
Ensembl peptide - ENSP00000413190
Ensembl peptide - ENSP00000462310
NCBI entrez gene - 29098     See in Manteia.
OMIM - 607954
RefSeq - XM_005256618
RefSeq - NM_001177801
RefSeq - NM_001177802
RefSeq - NM_016492
RefSeq Peptide - NP_001171273
RefSeq Peptide - NP_001317056
RefSeq Peptide - NP_057576
RefSeq Peptide - NP_001171272
swissprot - Q9HD47
Ensembl - ENSG00000108961
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rangrfENSDARG00000098786Danio rerio
 Q9JIB0ENSMUSG00000032892Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007681  Ran-interacting Mog1 protein
 IPR016123  Mog1/PsbP, alpha/beta/alpha sandwich


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002027 regulation of heart rate TAS
 biological_processGO:0003254 regulation of membrane depolarization IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0032527 protein exit from endoplasmic reticulum IMP
 biological_processGO:0042391 regulation of membrane potential IDA
 biological_processGO:0090226 regulation of microtubule nucleation by Ran protein signal transduction IMP
 biological_processGO:0098905 regulation of bundle of His cell action potential IMP
 biological_processGO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction IMP
 biological_processGO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential TAS
 biological_processGO:1902305 regulation of sodium ion transmembrane transport IEA
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane IMP
 biological_processGO:2000010 positive regulation of protein localization to cell surface IMP
 biological_processGO:2000649 regulation of sodium ion transmembrane transporter activity IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005791 rough endoplasmic reticulum IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IC
 cellular_componentGO:0005901 caveola IDA
 cellular_componentGO:0014704 intercalated disc IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity ISS
 molecular_functionGO:0005087 Ran guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0008536 Ran GTPase binding IEA
 molecular_functionGO:0008565 protein transporter activity IMP
 molecular_functionGO:0017080 sodium channel regulator activity IEA
 molecular_functionGO:0044325 ion channel binding IEA


Pathways (from Reactome)
Pathway description
Phase 0 - rapid depolarisation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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