ENSG00000109684


Homo sapiens

Features
Gene ID: ENSG00000109684
  
Biological name :CLNK
  
Synonyms : CLNK / cytokine dependent hematopoietic cell linker / Q7Z7G1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: p16.1
Gene start: 10486395
Gene end: 10684865
  
Corresponding Affymetrix probe sets: 1562587_at (Human Genome U133 Plus 2.0 Array)   1570239_a_at (Human Genome U133 Plus 2.0 Array)   241483_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000226951
Ensembl peptide - ENSP00000427256
Ensembl peptide - ENSP00000427208
Ensembl peptide - ENSP00000390744
NCBI entrez gene - 116449     See in Manteia.
OMIM - 611434
RefSeq - XM_011513775
RefSeq - XM_017007685
RefSeq - NM_052964
RefSeq - XM_017007684
RefSeq Peptide - NP_443196
swissprot - Q7Z7G1
swissprot - D6RJB9
swissprot - A0A0A0MSJ4
Ensembl - ENSG00000109684
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01088229.1ENSDARG00000091321Danio rerio
 ClnkENSMUSG00000039315Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LCP2 / Q13094 / lymphocyte cytosolic protein 2ENSG0000004346222
BLNK / Q8WV28 / B cell linkerENSG0000009558519
SH2D6 / Q7Z4S9 / SH2 domain containing 6ENSG000001522927


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR036860  SH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response IBA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IDA
 cellular_componentGO:0005622 intracellular NAS
 molecular_functionGO:0005070 SH3/SH2 adaptor activity NAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr