ENSG00000110076


Homo sapiens

Features
Gene ID: ENSG00000110076
  
Biological name :NRXN2
  
Synonyms : neurexin 2 / NRXN2 / P58401 / Q9P2S2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q13.1
Gene start: 64606174
Gene end: 64723188
  
Corresponding Affymetrix probe sets: 209982_s_at (Human Genome U133 Plus 2.0 Array)   209983_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000412211
Ensembl peptide - ENSP00000407374
Ensembl peptide - ENSP00000411271
Ensembl peptide - ENSP00000265459
Ensembl peptide - ENSP00000301894
Ensembl peptide - ENSP00000366774
Ensembl peptide - ENSP00000366782
Ensembl peptide - ENSP00000386416
Ensembl peptide - ENSP00000388971
NCBI entrez gene - 9379     See in Manteia.
OMIM - 600566
RefSeq - XM_017018578
RefSeq - XM_017018568
RefSeq - XM_017018569
RefSeq - XM_017018570
RefSeq - XM_017018571
RefSeq - XM_017018572
RefSeq - XM_017018573
RefSeq - XM_017018574
RefSeq - XM_017018575
RefSeq - XM_017018576
RefSeq - XM_017018577
RefSeq - NM_015080
RefSeq - NM_138732
RefSeq - NM_138734
RefSeq - XM_005274400
RefSeq - XM_005274401
RefSeq - XM_005274402
RefSeq - XM_011545370
RefSeq - XM_011545371
RefSeq - XM_011545373
RefSeq - XM_011545375
RefSeq - XM_011545385
RefSeq - XM_017018563
RefSeq - XM_017018564
RefSeq - XM_017018565
RefSeq - XM_017018566
RefSeq - XM_017018567
RefSeq Peptide - NP_055895
RefSeq Peptide - NP_620060
RefSeq Peptide - NP_620063
swissprot - H7C3J4
swissprot - P58401
swissprot - H7BZC7
swissprot - G5E9G7
swissprot - Q9P2S2
swissprot - H7C2R8
swissprot - H7C3D6
Ensembl - ENSG00000110076
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 neurexin 2ENSDARG00000113112Danio rerio
 nrxn2bENSDARG00000063150Danio rerio
 Nrxn2ENSMUSG00000033768Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NRXN3 / Q9HDB5 / Q9Y4C0 / neurexin 3ENSG0000002164561
NRXN1 / P58400 / Q9ULB1 / neurexin 1ENSG0000017991561
Q9C0A0 / CNTNAP4 / contactin associated protein like 4ENSG0000015291019
Q96NU0 / CNTNAP3B / contactin associated protein like 3BENSG0000015452918
Q9BZ76 / CNTNAP3 / contactin associated protein like 3ENSG0000010671418
Q8WYK1 / CNTNAP5 / contactin associated protein like 5ENSG0000015505218
Q9UHC6 / CNTNAP2 / contactin associated protein like 2ENSG0000017446917
P78357 / CNTNAP1 / contactin associated protein 1ENSG0000010879717
BX088645.1ENSG000002833787
AC104151.1ENSG000002618331


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001791  Laminin G domain
 IPR003585  Neurexin/syndecan/glycophorin C
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR027789  Syndecan/Neurexin domain
 IPR037440  Neurexin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007158 neuron cell-cell adhesion TAS
 biological_processGO:0007165 signal transduction ISS
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0007269 neurotransmitter secretion IEA
 biological_processGO:0007416 synapse assembly IEA
 biological_processGO:0030534 adult behavior IMP
 biological_processGO:0035176 social behavior IMP
 biological_processGO:0042297 vocal learning IMP
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0071625 vocalization behavior IMP
 biological_processGO:0097104 postsynaptic membrane assembly ISS
 biological_processGO:0097116 gephyrin clustering involved in postsynaptic density assembly ISS
 biological_processGO:0097118 neuroligin clustering involved in postsynaptic membrane assembly ISS
 biological_processGO:0097119 postsynaptic density protein 95 clustering ISS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity ISS
 molecular_functionGO:0005246 calcium channel regulator activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050839 cell adhesion molecule binding ISS
 molecular_functionGO:0097109 neuroligin family protein binding ISS


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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