ENSG00000110344


Homo sapiens

Features
Gene ID: ENSG00000110344
  
Biological name :UBE4A
  
Synonyms : Q14139 / UBE4A / ubiquitination factor E4A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q23.3
Gene start: 118359585
Gene end: 118399211
  
Corresponding Affymetrix probe sets: 202038_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000387362
Ensembl peptide - ENSP00000438918
Ensembl peptide - ENSP00000252108
NCBI entrez gene - 9354     See in Manteia.
OMIM - 603753
RefSeq - NM_001204077
RefSeq - NM_004788
RefSeq Peptide - NP_001191006
RefSeq Peptide - NP_004779
swissprot - B7Z7P0
swissprot - Q14139
Ensembl - ENSG00000110344
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ube4aENSDARG00000040571Danio rerio
 UBE4AENSGALG00000031134Gallus gallus
 Ube4aENSMUSG00000059890Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UBE4B / O95155 / ubiquitination factor E4BENSG0000013093923


Protein motifs (from Interpro)
Interpro ID Name
 IPR003613  U box domain
 IPR011989  Armadillo-like helical
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019474  Ubiquitin conjugation factor E4, core


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IBA
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0034450 ubiquitin-ubiquitin ligase activity IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr