ENSG00000130939


Homo sapiens

Features
Gene ID: ENSG00000130939
  
Biological name :UBE4B
  
Synonyms : O95155 / UBE4B / ubiquitination factor E4B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.22
Gene start: 10032832
Gene end: 10181239
  
Corresponding Affymetrix probe sets: 202316_x_at (Human Genome U133 Plus 2.0 Array)   202317_s_at (Human Genome U133 Plus 2.0 Array)   210685_s_at (Human Genome U133 Plus 2.0 Array)   215533_s_at (Human Genome U133 Plus 2.0 Array)   226746_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000253251
Ensembl peptide - ENSP00000366358
Ensembl peptide - ENSP00000467258
Ensembl peptide - ENSP00000468178
Ensembl peptide - ENSP00000343001
NCBI entrez gene - 10277     See in Manteia.
OMIM - 613565
RefSeq - XM_017000036
RefSeq - NM_006048
RefSeq - XM_005263422
RefSeq - XM_011540488
RefSeq - XM_011540489
RefSeq - XM_011540490
RefSeq - XM_017000035
RefSeq - NM_001105562
RefSeq Peptide - NP_001099032
RefSeq Peptide - NP_006039
swissprot - K7EP75
swissprot - K7ERA7
swissprot - O95155
swissprot - B1AQ61
Ensembl - ENSG00000130939
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ube4bENSDARG00000037017Danio rerio
 UBE4BENSGALG00000002649Gallus gallus
 Ube4bENSMUSG00000028960Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UBE4A / Q14139 / ubiquitination factor E4AENSG0000011034419


Protein motifs (from Interpro)
Interpro ID Name
 IPR003613  U box domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019474  Ubiquitin conjugation factor E4, core


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IEA
 biological_processGO:0003222 ventricular trabecula myocardium morphogenesis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0006513 protein monoubiquitination IEA
 biological_processGO:0008626 granzyme-mediated apoptotic signaling pathway IDA
 biological_processGO:0009411 response to UV IDA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IBA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0034976 response to endoplasmic reticulum stress IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0044257 cellular protein catabolic process IEA
 biological_processGO:0051865 protein autoubiquitination IEA
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0034450 ubiquitin-ubiquitin ligase activity IEA
 molecular_functionGO:0051117 ATPase binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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