ENSG00000111229


Homo sapiens

Features
Gene ID: ENSG00000111229
  
Biological name :ARPC3
  
Synonyms : actin related protein 2/3 complex subunit 3 / ARPC3 / O15145
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.11
Gene start: 110434825
Gene end: 110450422
  
Corresponding Affymetrix probe sets: 1565705_x_at (Human Genome U133 Plus 2.0 Array)   208736_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000446598
Ensembl peptide - ENSP00000228825
Ensembl peptide - ENSP00000413221
NCBI entrez gene - 10094     See in Manteia.
OMIM - 604225
RefSeq - NM_001287222
RefSeq - NM_001278556
RefSeq Peptide - NP_001265485
RefSeq Peptide - NP_001274151
swissprot - O15145
swissprot - C9JZD1
swissprot - F8VR50
Ensembl - ENSG00000111229
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arpc3ENSDARG00000057882Danio rerio
 ARPC3ENSGALG00000003820Gallus gallus
 Arpc3ENSMUSG00000029465Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007204  Actin-related protein 2/3 complex subunit 3
 IPR036753  Actin-related protein 2/3 complex subunit 3 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030833 regulation of actin filament polymerization IEA
 biological_processGO:0034314 Arp2/3 complex-mediated actin nucleation IEA
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0048013 ephrin receptor signaling pathway TAS
 biological_processGO:0061024 membrane organization TAS
 biological_processGO:0070358 actin polymerization-dependent cell motility TAS
 biological_processGO:1990090 cellular response to nerve growth factor stimulus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005885 Arp2/3 protein complex IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0015629 actin cytoskeleton TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0031252 cell leading edge IEA
 cellular_componentGO:0031941 filamentous actin IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0061850 growth cone leading edge IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0051015 actin filament binding IDA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
EPHB-mediated forward signaling
RHO GTPases Activate WASPs and WAVEs
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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