ENSG00000111348


Homo sapiens

Features
Gene ID: ENSG00000111348
  
Biological name :ARHGDIB
  
Synonyms : ARHGDIB / P52566 / Rho GDP dissociation inhibitor beta
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p12.3
Gene start: 14942017
Gene end: 14961728
  
Corresponding Affymetrix probe sets: 1555811_at (Human Genome U133 Plus 2.0 Array)   1555812_a_at (Human Genome U133 Plus 2.0 Array)   201288_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000445450
Ensembl peptide - ENSP00000440560
Ensembl peptide - ENSP00000437454
Ensembl peptide - ENSP00000228945
Ensembl peptide - ENSP00000445185
Ensembl peptide - ENSP00000445263
Ensembl peptide - ENSP00000444860
NCBI entrez gene - 397     See in Manteia.
OMIM - 602843
RefSeq - NM_001321423
RefSeq - NM_001175
RefSeq - NM_001321420
RefSeq - NM_001321421
RefSeq - NM_001321422
RefSeq Peptide - NP_001166
RefSeq Peptide - NP_001308352
RefSeq Peptide - NP_001308351
RefSeq Peptide - NP_001308350
RefSeq Peptide - NP_001308349
swissprot - P52566
swissprot - A0A024RAS5
swissprot - F5H2R5
swissprot - F5H3P3
swissprot - F5H6Q0
swissprot - H0YGX7
Ensembl - ENSG00000111348
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgdigENSDARG00000004034Danio rerio
 ARHGDIBENSGALG00000011738Gallus gallus
 Q61599ENSMUSG00000030220Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P52565 / ARHGDIA / Rho GDP dissociation inhibitor alphaENSG0000014152257
Q99819 / ARHGDIG / Rho GDP dissociation inhibitor gammaENSG0000024217355


Protein motifs (from Interpro)
Interpro ID Name
 IPR000406  Rho protein GDP-dissociation inhibitor
 IPR014756  Immunoglobulin E-set
 IPR024792  Rho GDP-dissociation inhibitor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007162 negative regulation of cell adhesion TAS
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0035023 regulation of Rho protein signal transduction IMP
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0050790 regulation of catalytic activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 biological_processGO:0071461 cellular response to redox state IEA
 biological_processGO:1901164 negative regulation of trophoblast cell migration IDA
 biological_processGO:2000249 regulation of actin cytoskeleton reorganization IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003924 GTPase activity IMP
 molecular_functionGO:0005094 Rho GDP-dissociation inhibitor activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0048365 Rac GTPase binding IDA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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