ENSG00000242173


Homo sapiens

Features
Gene ID: ENSG00000242173
  
Biological name :ARHGDIG
  
Synonyms : ARHGDIG / Q99819 / Rho GDP dissociation inhibitor gamma
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.3
Gene start: 268727
Gene end: 283010
  
Corresponding Affymetrix probe sets: 206888_s_at (Human Genome U133 Plus 2.0 Array)   206889_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000219409
Ensembl peptide - ENSP00000410541
Ensembl peptide - ENSP00000408037
Ensembl peptide - ENSP00000404435
Ensembl peptide - ENSP00000397395
NCBI entrez gene - 398     See in Manteia.
OMIM - 602844
RefSeq - NM_001176
RefSeq Peptide - NP_001167
swissprot - A2ID99
swissprot - F1T0H7
swissprot - C9JR26
swissprot - Q99819
swissprot - C9J9L9
swissprot - C9J3B5
Ensembl - ENSG00000242173
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARHGDIGENSGALG00000036819Gallus gallus
 Q62160ENSMUSG00000073433Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P52566 / ARHGDIB / Rho GDP dissociation inhibitor betaENSG0000011134849
P52565 / ARHGDIA / Rho GDP dissociation inhibitor alphaENSG0000014152245


Protein motifs (from Interpro)
Interpro ID Name
 IPR000406  Rho protein GDP-dissociation inhibitor
 IPR014756  Immunoglobulin E-set
 IPR024792  Rho GDP-dissociation inhibitor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007162 negative regulation of cell adhesion TAS
 biological_processGO:0007266 Rho protein signal transduction TAS
 biological_processGO:0032880 regulation of protein localization IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0050790 regulation of catalytic activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle TAS
 molecular_functionGO:0005092 GDP-dissociation inhibitor activity IEA
 molecular_functionGO:0005094 Rho GDP-dissociation inhibitor activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030695 GTPase regulator activity IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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