ENSG00000111536


Homo sapiens

Features
Gene ID: ENSG00000111536
  
Biological name :IL26
  
Synonyms : IL26 / interleukin 26 / Q9NPH9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q15
Gene start: 68201351
Gene end: 68225821
  
Corresponding Affymetrix probe sets: 221111_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000229134
NCBI entrez gene - 55801     See in Manteia.
OMIM - 605679
RefSeq - NM_018402
RefSeq Peptide - NP_060872
swissprot - Q9NPH9
Ensembl - ENSG00000111536
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IL26ENSGALG00000037779Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009079  Four-helical cytokine-like, core
 IPR020423  Interleukin-10, conserved site
 IPR020443  Interleukin-10/19/20/22/24/26 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0046427 positive regulation of JAK-STAT cascade IDA
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IDA
 biological_processGO:0050715 positive regulation of cytokine secretion IDA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IDA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0005125 cytokine activity IEA


Pathways (from Reactome)
Pathway description
Interleukin-20 family signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000105397 TYK2 / P29597 / tyrosine kinase 2  / reaction / complex
 ENSG00000168610 STAT3 / P40763 / signal transducer and activator of transcription 3  / complex
 ENSG00000243646 IL10RB / Q08334 / interleukin 10 receptor subunit beta  / complex / reaction
 ENSG00000162434 JAK1 / P23458 / Janus kinase 1  / complex
 ENSG00000016402 IL20RA / Q9UHF4 / interleukin 20 receptor subunit alpha  / complex
 ENSG00000115415 STAT1 / P42224 / signal transducer and activator of transcription 1  / complex






 

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