ENSG00000111684


Homo sapiens

Features
Gene ID: ENSG00000111684
  
Biological name :LPCAT3
  
Synonyms : LPCAT3 / lysophosphatidylcholine acyltransferase 3 / Q6P1A2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p13.31
Gene start: 6976186
Gene end: 7018510
  
Corresponding Affymetrix probe sets: 202793_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000440550
Ensembl peptide - ENSP00000443166
Ensembl peptide - ENSP00000442454
Ensembl peptide - ENSP00000261407
Ensembl peptide - ENSP00000437827
Ensembl peptide - ENSP00000438765
NCBI entrez gene - 10162     See in Manteia.
OMIM - 611950
RefSeq - NM_005768
RefSeq Peptide - NP_005759
swissprot - F5H680
swissprot - F5H7K7
swissprot - B7Z3N5
swissprot - Q6P1A2
swissprot - F5GYT3
swissprot - F5H0M4
Ensembl - ENSG00000111684
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lpcat3ENSDARG00000075178Danio rerio
 LPCAT3ENSGALG00000014570Gallus gallus
 Lpcat3ENSMUSG00000004270Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MBOAT2 / Q6ZWT7 / membrane bound O-acyltransferase domain containing 2ENSG0000014379722
MBOAT1 / Q6ZNC8 / membrane bound O-acyltransferase domain containing 1ENSG0000017219722
MBOAT7 / Q96N66 / membrane bound O-acyltransferase domain containing 7ENSG0000012550517
MBOAT4 / Q96T53 / membrane bound O-acyltransferase domain containing 4ENSG0000017766915


Protein motifs (from Interpro)
Interpro ID Name
 IPR004299  Membrane bound O-acyl transferase, MBOAT


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006644 phospholipid metabolic process IEA
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 biological_processGO:0036150 phosphatidylserine acyl-chain remodeling TAS
 biological_processGO:0036151 phosphatidylcholine acyl-chain remodeling TAS
 biological_processGO:0036152 phosphatidylethanolamine acyl-chain remodeling TAS
 biological_processGO:0097006 regulation of plasma lipoprotein particle levels IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity TAS
 molecular_functionGO:0047184 1-acylglycerophosphocholine O-acyltransferase activity IMP


Pathways (from Reactome)
Pathway description
Acyl chain remodelling of PC
Acyl chain remodelling of PS
Acyl chain remodelling of PE


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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