ENSG00000111728


Homo sapiens

Features
Gene ID: ENSG00000111728
  
Biological name :ST8SIA1
  
Synonyms : Q92185 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 / ST8SIA1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p12.1
Gene start: 22063773
Gene end: 22437041
  
Corresponding Affymetrix probe sets: 1569788_at (Human Genome U133 Plus 2.0 Array)   210073_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000379353
Ensembl peptide - ENSP00000384467
Ensembl peptide - ENSP00000440292
Ensembl peptide - ENSP00000441707
Ensembl peptide - ENSP00000444999
Ensembl peptide - ENSP00000261197
Ensembl peptide - ENSP00000370832
NCBI entrez gene - 6489     See in Manteia.
OMIM - 601123
RefSeq - NM_003034
RefSeq - NM_001304450
RefSeq Peptide - NP_001291379
RefSeq Peptide - NP_003025
swissprot - Q92185
swissprot - F8WCS8
swissprot - H0YFU1
swissprot - H0YG41
swissprot - H0YGV9
swissprot - Q86X71
Ensembl - ENSG00000111728
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 st8sia1ENSDARG00000098221Danio rerio
 ST8SIA1ENSGALG00000013211Gallus gallus
 Q64687ENSMUSG00000030283Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P61647 / ST8SIA6 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6ENSG0000014848837
O15466 / ST8SIA5 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5ENSG0000010163837
O43173 / ST8SIA3 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3ENSG0000017751130
Q92186 / ST8SIA2 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2ENSG0000014055728
Q92187 / ST8SIA4 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4ENSG0000011353227


Protein motifs (from Interpro)
Interpro ID Name
 IPR001675  Glycosyl transferase family 29
 IPR012163  Sialyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process TAS
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0006688 glycosphingolipid biosynthetic process TAS
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0034605 cellular response to heat IEA
 biological_processGO:0097503 sialylation IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity IEA
 molecular_functionGO:0008373 sialyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
Sialic acid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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