ENSG00000140557


Homo sapiens

Features
Gene ID: ENSG00000140557
  
Biological name :ST8SIA2
  
Synonyms : Q92186 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 / ST8SIA2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q26.1
Gene start: 92393828
Gene end: 92468728
  
Corresponding Affymetrix probe sets: 221285_at (Human Genome U133 Plus 2.0 Array)   239537_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000437382
Ensembl peptide - ENSP00000450851
Ensembl peptide - ENSP00000268164
NCBI entrez gene - 8128     See in Manteia.
OMIM - 602546
RefSeq - XM_017022643
RefSeq - NM_001330416
RefSeq - NM_006011
RefSeq - XM_017022642
RefSeq Peptide - NP_001317345
RefSeq Peptide - NP_006002
swissprot - B2R9U8
swissprot - C6G488
swissprot - G3V2T1
swissprot - Q92186
Ensembl - ENSG00000140557
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 st8sia2ENSDARG00000018788Danio rerio
 ST8SIA2ENSGALG00000006882Gallus gallus
 O35696ENSMUSG00000025789Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q92187 / ST8SIA4 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4ENSG0000011353255
O43173 / ST8SIA3 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3ENSG0000017751133
O15466 / ST8SIA5 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5ENSG0000010163827
P61647 / ST8SIA6 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6ENSG0000014848827
Q92185 / ST8SIA1 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1ENSG0000011172827


Protein motifs (from Interpro)
Interpro ID Name
 IPR001675  Glycosyl transferase family 29
 IPR012163  Sialyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001574 ganglioside biosynthetic process IDA
 biological_processGO:0005975 carbohydrate metabolic process TAS
 biological_processGO:0006464 cellular protein modification process TAS
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006491 N-glycan processing IDA
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0009311 oligosaccharide metabolic process IDA
 biological_processGO:0097503 sialylation IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0055037 recycling endosome IEA
 molecular_functionGO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity IDA
 molecular_functionGO:0008373 sialyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0033691 sialic acid binding IC


Pathways (from Reactome)
Pathway description
Sialic acid metabolism
NCAM1 interactions
N-Glycan antennae elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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