ENSG00000111796


Homo sapiens

Features
Gene ID: ENSG00000111796
  
Biological name :KLRB1
  
Synonyms : killer cell lectin like receptor B1 / KLRB1 / Q12918
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p13.31
Gene start: 9594551
Gene end: 9607886
  
Corresponding Affymetrix probe sets: 214470_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000229402
NCBI entrez gene - 3820     See in Manteia.
OMIM - 602890
RefSeq - NM_002258
RefSeq Peptide - NP_002249
swissprot - Q12918
Ensembl - ENSG00000111796
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BLEC2ENSGALG00000000136Gallus gallus
 Gm44511ENSMUSG00000107872Mus musculus
 Klrb1ENSMUSG00000079299Mus musculus
 Klrb1aENSMUSG00000030361Mus musculus
 Klrb1bENSMUSG00000079298Mus musculus
 Klrb1cENSMUSG00000030325Mus musculus
 Klrb1fENSMUSG00000030154Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLRF1 / Q9NZS2 / killer cell lectin like receptor F1ENSG0000015004526
KLRF2 / D3W0D1 / killer cell lectin like receptor F2ENSG0000025679723


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR033992  Natural killer cell receptor-like, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0050776 regulation of immune response TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030246 carbohydrate binding TAS


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000111796 KLRB1 / Q12918 / killer cell lectin like receptor B1  / complex
 ENSG00000069493 CLEC2D / Q9UHP7 / C-type lectin domain family 2 member D  / complex / reaction






 

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