ENSG00000112139


Homo sapiens

Features
Gene ID: ENSG00000112139
  
Biological name :MDGA1
  
Synonyms : MAM domain containing glycosylphosphatidylinositol anchor 1 / MDGA1 / Q8NFP4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.2
Gene start: 37630679
Gene end: 37699306
  
Corresponding Affymetrix probe sets: 232237_at (Human Genome U133 Plus 2.0 Array)   238543_x_at (Human Genome U133 Plus 2.0 Array)   242757_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000421510
Ensembl peptide - ENSP00000427645
Ensembl peptide - ENSP00000425911
Ensembl peptide - ENSP00000422042
Ensembl peptide - ENSP00000393330
Ensembl peptide - ENSP00000402584
NCBI entrez gene - 266727     See in Manteia.
OMIM - 609626
RefSeq - XM_017010734
RefSeq - NM_153487
RefSeq - XM_006715056
RefSeq Peptide - NP_705691
swissprot - H0YA23
swissprot - D6RHU8
swissprot - Q8NFP4
swissprot - D6RFG6
swissprot - H0Y4Q2
Ensembl - ENSG00000112139
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mdga1ENSDARG00000074376Danio rerio
 MDGA1ENSGALG00000010145Gallus gallus
 Mdga1ENSMUSG00000043557Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MDGA2 / Q7Z553 / MAM domain containing glycosylphosphatidylinositol anchor 2ENSG0000013991553
MAMDC4 / Q6UXC1 / MAM domain containing 4ENSG0000017794317
MALRD1 / Q5VYJ5 / MAM and LDL receptor class A domain containing 1ENSG0000020474014
MAMDC2 / Q7Z304 / MAM domain containing 2ENSG0000016507212


Protein motifs (from Interpro)
Interpro ID Name
 IPR000998  MAM domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration ISS
 biological_processGO:0006501 C-terminal protein lipidation TAS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007420 brain development ISS
 biological_processGO:0021527 spinal cord association neuron differentiation ISS
 biological_processGO:0030154 cell differentiation IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0046658 anchored component of plasma membrane ISS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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