ENSG00000204740


Homo sapiens

Features
Gene ID: ENSG00000204740
  
Biological name :MALRD1
  
Synonyms : MALRD1 / MAM and LDL receptor class A domain containing 1 / Q5VYJ5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: p12.31
Gene start: 19048771
Gene end: 19790401
  
Corresponding Affymetrix probe sets: 242660_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000412763
Ensembl peptide - ENSP00000366476
Ensembl peptide - ENSP00000366477
Ensembl peptide - ENSP00000403218
NCBI entrez gene - 340895     See in Manteia.
OMIM - 617715
RefSeq - XM_017016186
RefSeq - XM_011519455
RefSeq - XM_017016182
RefSeq - XM_017016183
RefSeq - XM_017016184
RefSeq - XM_017016185
RefSeq - NM_001142308
RefSeq - XM_011519453
RefSeq - XM_011519454
RefSeq Peptide - NP_001135780
swissprot - H0Y3D6
swissprot - B7ZBP3
swissprot - Q5VYJ5
swissprot - U5GXS0
Ensembl - ENSG00000204740
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 malrd1ENSDARG00000090618Danio rerio
 MALRD1ENSGALG00000008498Gallus gallus
 A2AJX4ENSMUSG00000075520Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAMDC4 / Q6UXC1 / MAM domain containing 4ENSG0000017794314
MDGA2 / Q7Z553 / MAM domain containing glycosylphosphatidylinositol anchor 2ENSG000001399157
MAMDC2 / Q7Z304 / MAM domain containing 2ENSG000001650727
MDGA1 / Q8NFP4 / MAM domain containing glycosylphosphatidylinositol anchor 1ENSG000001121396


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR000998  MAM domain
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR013032  EGF-like, conserved site
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR023415  Low-density lipoprotein (LDL) receptor class A, conserved site
 IPR036055  LDL receptor-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042632 cholesterol homeostasis IEA
 biological_processGO:0070858 negative regulation of bile acid biosynthetic process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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