ENSG00000112379


Homo sapiens

Features
Gene ID: ENSG00000112379
  
Biological name :ARFGEF3
  
Synonyms : ARFGEF3 / ARFGEF family member 3 / Q5TH69
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q23.3
Gene start: 138161921
Gene end: 138344663
  
Corresponding Affymetrix probe sets: 228051_at (Human Genome U133 Plus 2.0 Array)   231856_at (Human Genome U133 Plus 2.0 Array)   236037_at (Human Genome U133 Plus 2.0 Array)   242098_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000251691
NCBI entrez gene - 57221     See in Manteia.
OMIM - 617411
RefSeq - NM_020340
RefSeq Peptide - NP_065073
swissprot - Q5TH69
Ensembl - ENSG00000112379
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arfgef3ENSDARG00000077656Danio rerio
 ARFGEF3ENSGALG00000013846Gallus gallus
 Q3UGY8ENSMUSG00000019852Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000904  Sec7 domain
 IPR011989  Armadillo-like helical
 IPR015403  Sec7, C-terminal
 IPR016024  Armadillo-type fold
 IPR023394  Sec7, C-terminal domain superfamily
 IPR032629  Mon2, dimerisation and cyclophilin-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010923 negative regulation of phosphatase activity IDA
 biological_processGO:0032012 regulation of ARF protein signal transduction IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030133 transport vesicle IEA
 cellular_componentGO:0030658 transport vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005086 ARF guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005488 binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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