ENSG00000112419


Homo sapiens

Features
Gene ID: ENSG00000112419
  
Biological name :PHACTR2
  
Synonyms : O75167 / PHACTR2 / phosphatase and actin regulator 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q24.2
Gene start: 143536845
Gene end: 143831185
  
Corresponding Affymetrix probe sets: 204047_s_at (Human Genome U133 Plus 2.0 Array)   204048_s_at (Human Genome U133 Plus 2.0 Array)   204049_s_at (Human Genome U133 Plus 2.0 Array)   227947_at (Human Genome U133 Plus 2.0 Array)   244774_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000442153
Ensembl peptide - ENSP00000356556
Ensembl peptide - ENSP00000356554
Ensembl peptide - ENSP00000305530
Ensembl peptide - ENSP00000402449
Ensembl peptide - ENSP00000417038
Ensembl peptide - ENSP00000381067
Ensembl peptide - ENSP00000391763
NCBI entrez gene - 9749     See in Manteia.
OMIM - 608724
RefSeq - NM_014721
RefSeq - NM_001100164
RefSeq - NM_001100165
RefSeq - NM_001100166
RefSeq Peptide - NP_001093634
RefSeq Peptide - NP_055536
RefSeq Peptide - NP_001093636
RefSeq Peptide - NP_001093635
swissprot - O75167
swissprot - F5H858
swissprot - F6TH74
swissprot - H9KVA6
swissprot - J3KP75
Ensembl - ENSG00000112419
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phactr2ENSDARG00000027172Danio rerio
 PHACTR2ENSGALG00000013768Gallus gallus
 Phactr2ENSMUSG00000062866Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8IZ21 / PHACTR4 / phosphatase and actin regulator 4ENSG0000020413840
Q9C0D0 / PHACTR1 / phosphatase and actin regulator 1ENSG0000011213733
Q96KR7 / PHACTR3 / phosphatase and actin regulator 3ENSG0000008749531


Protein motifs (from Interpro)
Interpro ID Name
 IPR004018  RPEL repeat
 IPR029991  Phosphatase and actin regulator 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031092 platelet alpha granule membrane TAS
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0004864 protein phosphatase inhibitor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Platelet degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr