ENSG00000204138


Homo sapiens

Features
Gene ID: ENSG00000204138
  
Biological name :PHACTR4
  
Synonyms : PHACTR4 / phosphatase and actin regulator 4 / Q8IZ21
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p35.3
Gene start: 28369582
Gene end: 28500369
  
Corresponding Affymetrix probe sets: 219235_s_at (Human Genome U133 Plus 2.0 Array)   226823_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000487630
Ensembl peptide - ENSP00000362945
Ensembl peptide - ENSP00000488137
Ensembl peptide - ENSP00000488693
Ensembl peptide - ENSP00000488359
Ensembl peptide - ENSP00000362942
NCBI entrez gene - 65979     See in Manteia.
OMIM - 608726
RefSeq - XM_017002173
RefSeq - XM_017002163
RefSeq - XM_017002164
RefSeq - XM_017002165
RefSeq - XM_017002166
RefSeq - XM_017002167
RefSeq - XM_017002168
RefSeq - XM_017002169
RefSeq - XM_017002170
RefSeq - XM_017002171
RefSeq - XM_017002172
RefSeq - NM_001048183
RefSeq - NM_001350158
RefSeq - NM_001350159
RefSeq - NM_001350160
RefSeq - NM_001350161
RefSeq - NM_023923
RefSeq - XM_005245970
RefSeq - XM_017002157
RefSeq - XM_017002158
RefSeq - XM_017002159
RefSeq - XM_017002160
RefSeq - XM_017002161
RefSeq - XM_017002162
RefSeq Peptide - NP_001337087
RefSeq Peptide - NP_001337089
RefSeq Peptide - NP_001337090
RefSeq Peptide - NP_076412
RefSeq Peptide - NP_001041648
RefSeq Peptide - NP_001337088
swissprot - A0A0J9YWV8
swissprot - A0A0J9YY52
swissprot - Q8IZ21
swissprot - A0A0J9YVR0
Ensembl - ENSG00000204138
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phactr4aENSDARG00000015552Danio rerio
 Q6PEI3ENSDARG00000032221Danio rerio
 PHACTR4ENSGALG00000042485Gallus gallus
 Q501J7ENSMUSG00000066043Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O75167 / PHACTR2 / phosphatase and actin regulator 2ENSG0000011241936
Q9C0D0 / PHACTR1 / phosphatase and actin regulator 1ENSG0000011213731
Q96KR7 / PHACTR3 / phosphatase and actin regulator 3ENSG0000008749528


Protein motifs (from Interpro)
Interpro ID Name
 IPR004018  RPEL repeat
 IPR029984  Phosphatase and actin regulator 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001755 neural crest cell migration IEA
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0007266 Rho protein signal transduction IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0048484 enteric nervous system development IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0061386 closure of optic fissure IEA
 biological_processGO:2001045 negative regulation of integrin-mediated signaling pathway IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030027 lamellipodium ISS
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003779 actin binding ISS
 molecular_functionGO:0004864 protein phosphatase inhibitor activity IEA
 molecular_functionGO:0008157 protein phosphatase 1 binding ISS
 molecular_functionGO:0019888 protein phosphatase regulator activity IEA
 molecular_functionGO:0072542 protein phosphatase activator activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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