ENSG00000112983


Homo sapiens

Features
Gene ID: ENSG00000112983
  
Biological name :BRD8
  
Synonyms : BRD8 / bromodomain containing 8 / Q9H0E9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q31.2
Gene start: 138139766
Gene end: 138178986
  
Corresponding Affymetrix probe sets: 202227_s_at (Human Genome U133 Plus 2.0 Array)   210352_at (Human Genome U133 Plus 2.0 Array)   242265_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000420884
Ensembl peptide - ENSP00000414625
Ensembl peptide - ENSP00000426385
Ensembl peptide - ENSP00000427475
Ensembl peptide - ENSP00000427126
Ensembl peptide - ENSP00000230901
Ensembl peptide - ENSP00000254900
Ensembl peptide - ENSP00000384845
Ensembl peptide - ENSP00000392646
Ensembl peptide - ENSP00000394330
Ensembl peptide - ENSP00000396487
Ensembl peptide - ENSP00000398067
Ensembl peptide - ENSP00000398084
Ensembl peptide - ENSP00000398676
Ensembl peptide - ENSP00000398873
Ensembl peptide - ENSP00000407129
Ensembl peptide - ENSP00000407414
NCBI entrez gene - 10902     See in Manteia.
OMIM - 602848
RefSeq - XM_017008976
RefSeq - NM_001164326
RefSeq - NM_001300961
RefSeq - NM_001300962
RefSeq - NM_001300966
RefSeq - NM_006696
RefSeq - NM_139199
RefSeq - XM_005271855
RefSeq - XM_005271856
RefSeq - XM_005271857
RefSeq - XM_005271859
RefSeq - XM_005271860
RefSeq - XM_005271861
RefSeq - XM_011543109
RefSeq - XM_011543110
RefSeq - XM_017008969
RefSeq - XM_017008970
RefSeq - XM_017008971
RefSeq - XM_017008972
RefSeq - XM_017008973
RefSeq - XM_017008974
RefSeq - XM_017008975
RefSeq Peptide - NP_006687
RefSeq Peptide - NP_631938
RefSeq Peptide - NP_001287891
RefSeq Peptide - NP_001287895
RefSeq Peptide - NP_001157798
RefSeq Peptide - NP_001287890
swissprot - H0YA84
swissprot - H0YAH7
swissprot - H7C026
swissprot - H7C127
swissprot - D6RID0
swissprot - H7C179
swissprot - H7C2P4
swissprot - Q9H0E9
swissprot - B5MCW3
swissprot - H7C128
swissprot - C9JV05
swissprot - F8WBH2
swissprot - F8WCS7
swissprot - F8WDX5
swissprot - H0Y8F9
Ensembl - ENSG00000112983
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 brd8ENSDARG00000025071Danio rerio
 BRD8ENSDARG00000055999Danio rerio
 BRD8ENSGALG00000037646Gallus gallus
 Brd8ENSMUSG00000003778Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001487  Bromodomain
 IPR036427  Bromodomain-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0040008 regulation of growth IEA
 biological_processGO:0043967 histone H4 acetylation IDA
 biological_processGO:0043968 histone H2A acetylation IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0000812 Swr1 complex IDA
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0035267 NuA4 histone acetyltransferase complex IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0004887 thyroid hormone receptor activity TAS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
HATs acetylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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