ENSG00000113272


Homo sapiens

Features
Gene ID: ENSG00000113272
  
Biological name :THG1L
  
Synonyms : Q9NWX6 / THG1L / tRNA-histidine guanylyltransferase 1 like
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q33.3
Gene start: 157731197
Gene end: 157741448
  
Corresponding Affymetrix probe sets: 219122_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000431090
Ensembl peptide - ENSP00000231198
Ensembl peptide - ENSP00000428387
NCBI entrez gene - 54974     See in Manteia.
RefSeq - XM_017009603
RefSeq - NM_001317824
RefSeq - NM_001317825
RefSeq - NM_001317826
RefSeq - NM_017872
RefSeq Peptide - NP_001304755
RefSeq Peptide - NP_060342
RefSeq Peptide - NP_001304754
RefSeq Peptide - NP_001304753
swissprot - H0YC78
swissprot - E5RIQ8
swissprot - Q9NWX6
Ensembl - ENSG00000113272
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 thg1lENSDARG00000038360Danio rerio
 THG1LENSGALG00000003722Gallus gallus
 Thg1lENSMUSG00000011254Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007537  tRNAHis guanylyltransferase Thg1
 IPR024956  tRNAHis guanylyltransferase catalytic domain
 IPR025845  Thg1 C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006400 tRNA modification IEA
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0051289 protein homotetramerization IDA
 biological_processGO:0099116 tRNA 5"-end processing IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000049 tRNA binding TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0005525 GTP binding IDA
 molecular_functionGO:0008193 tRNA guanylyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity EXP
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
tRNA modification in the nucleus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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