ENSG00000113732


Homo sapiens

Features
Gene ID: ENSG00000113732
  
Biological name :ATP6V0E1
  
Synonyms : ATP6V0E1 / ATPase H+ transporting V0 subunit e1 / O15342
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q35.1
Gene start: 172983757
Gene end: 173035445
  
Corresponding Affymetrix probe sets: 200096_s_at (Human Genome U133 Plus 2.0 Array)   201171_at (Human Genome U133 Plus 2.0 Array)   201172_x_at (Human Genome U133 Plus 2.0 Array)   214149_s_at (Human Genome U133 Plus 2.0 Array)   214150_x_at (Human Genome U133 Plus 2.0 Array)   214244_s_at (Human Genome U133 Plus 2.0 Array)   236527_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000429690
Ensembl peptide - ENSP00000430896
Ensembl peptide - ENSP00000265093
Ensembl peptide - ENSP00000427941
NCBI entrez gene - 8992     See in Manteia.
OMIM - 603931
RefSeq - NM_003945
RefSeq Peptide - NP_003936
swissprot - E5RHL5
swissprot - J3KN48
swissprot - O15342
Ensembl - ENSG00000113732
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9CQD8ENSMUSG00000015575Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8NHE4 / ATP6V0E2 / ATPase H+ transporting V0 subunit e2ENSG0000017113046


Protein motifs (from Interpro)
Interpro ID Name
 IPR008389  ATPase, V0 complex, subunit e1/e2
 IPR017385  ATPase, V0 complex, subunit e1/e2, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007035 vacuolar acidification ISS
 biological_processGO:0008286 insulin receptor signaling pathway TAS
 biological_processGO:0015991 ATP hydrolysis coupled proton transport IEA
 biological_processGO:0016241 regulation of macroautophagy NAS
 biological_processGO:0033572 transferrin transport TAS
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0090383 phagosome acidification TAS
 biological_processGO:1902600 proton transmembrane transport TAS
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030670 phagocytic vesicle membrane TAS
 cellular_componentGO:0033179 proton-transporting V-type ATPase, V0 domain IEA
 molecular_functionGO:0005215 transporter activity NAS
 molecular_functionGO:0015078 proton transmembrane transporter activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042625 ATPase coupled ion transmembrane transporter activity ISS
 molecular_functionGO:0046961 proton-transporting ATPase activity, rotational mechanism TAS


Pathways (from Reactome)
Pathway description
ROS, RNS production in phagocytes
Insulin receptor recycling
Transferrin endocytosis and recycling
Ion channel transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000171130 Q8NHE4 / ATP6V0E2 / ATPase H+ transporting V0 subunit e2  / complex






 

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